ID   RTM1_YEASX              Reviewed;         309 AA.
AC   P40113;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Protein RTM1;
GN   Name=RTM1;
OS   Saccharomyces cerevisiae (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 28383 / FL100 / VTT C-80102;
RX   PubMed=7672593; DOI=10.1093/genetics/140.3.945;
RA   Ness F., Aigle M.;
RT   "RTM1: a member of a new family of telomeric repeated genes in yeast.";
RL   Genetics 140:945-956(1995).
CC   -!- FUNCTION: Confers resistance to molasses (to a particular toxic element
CC       present in some molasses).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the lipid-translocating exporter (LTE) (TC
CC       9.A.26.1) family. {ECO:0000305}.
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DR   EMBL; U02618; AAA81533.1; -; Genomic_DNA.
DR   PIR; S59140; S59140.
DR   AlphaFoldDB; P40113; -.
DR   SGD; S000029677; RTM1.
DR   VEuPathDB; FungiDB:YER185W; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007568; RTA1.
DR   PANTHER; PTHR31465; PTHR31465; 1.
DR   Pfam; PF04479; RTA1; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Protein RTM1"
FT                   /id="PRO_0000097516"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  34435 MW;  1509824F4B9F839F CRC64;
     MSNDSSGSEW ELYRYTPSKG AAIALTVLFI VTTLIYSLQV VWDARKASKP EVDNPFDTPV
     DKCESITAIS LGENYKKLTV RSTFSAFIPL FFGCIMEIVG YIARAVSSSN TKEIAPYVIQ
     AVLLLIAPAL YAATIYMLFG RLLHVMRCES LMIVSSRFGT SFFVFGDVVS FCLQAAGGGL
     MATVNGRTTG SNLITAGLVI QIVFFGVFII NEFRFSYSVA RVCPFYRHIS KKWWFLNLTL
     MLSSILIMVR SIVRLVEFVE GYDGFIISHE YFIYVFDAVP MLLAAIVFIV GSFFGNIFTT
     ITECQSLKP