RTNLJ_ARATH
ID RTNLJ_ARATH Reviewed; 201 AA.
AC Q6NPD8; Q3EC00; Q9SHU8;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Reticulon-like protein B10;
DE Short=AtRTNLB10;
GN Name=RTNLB10; OrderedLocusNames=At2g15280; ORFNames=F27O10.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17604024; DOI=10.1016/j.febslet.2007.06.032;
RA Nziengui H., Bouhidel K., Pillon D., Der C., Marty F., Schoefs B.;
RT "Reticulon-like proteins in Arabidopsis thaliana: structural organization
RT and ER localization.";
RL FEBS Lett. 581:3356-3362(2007).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q9SH59}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6NPD8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6NPD8-2; Sequence=VSP_037007;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD26905.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007267; AAD26905.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC06381.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06382.1; -; Genomic_DNA.
DR EMBL; BX821446; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BT010716; AAR20773.1; -; mRNA.
DR EMBL; BT010986; AAR24764.1; -; mRNA.
DR PIR; A84527; A84527.
DR RefSeq; NP_179130.2; NM_127088.3. [Q6NPD8-1]
DR RefSeq; NP_973467.1; NM_201738.1. [Q6NPD8-2]
DR AlphaFoldDB; Q6NPD8; -.
DR BioGRID; 1376; 11.
DR IntAct; Q6NPD8; 11.
DR STRING; 3702.AT2G15280.1; -.
DR PaxDb; Q6NPD8; -.
DR PRIDE; Q6NPD8; -.
DR ProteomicsDB; 226678; -. [Q6NPD8-1]
DR EnsemblPlants; AT2G15280.1; AT2G15280.1; AT2G15280. [Q6NPD8-1]
DR EnsemblPlants; AT2G15280.2; AT2G15280.2; AT2G15280. [Q6NPD8-2]
DR GeneID; 816017; -.
DR Gramene; AT2G15280.1; AT2G15280.1; AT2G15280. [Q6NPD8-1]
DR Gramene; AT2G15280.2; AT2G15280.2; AT2G15280. [Q6NPD8-2]
DR KEGG; ath:AT2G15280; -.
DR Araport; AT2G15280; -.
DR TAIR; locus:2049077; AT2G15280.
DR eggNOG; KOG1792; Eukaryota.
DR HOGENOM; CLU_066344_0_2_1; -.
DR InParanoid; Q6NPD8; -.
DR OMA; RYQDHID; -.
DR OrthoDB; 1106300at2759; -.
DR PhylomeDB; Q6NPD8; -.
DR PRO; PR:Q6NPD8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q6NPD8; baseline and differential.
DR Genevisible; Q6NPD8; AT.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009617; P:response to bacterium; IEA:InterPro.
DR InterPro; IPR003388; Reticulon.
DR InterPro; IPR045064; Reticulon-like_plant.
DR PANTHER; PTHR10994; PTHR10994; 1.
DR Pfam; PF02453; Reticulon; 1.
DR PROSITE; PS50845; RETICULON; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Endoplasmic reticulum; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..201
FT /note="Reticulon-like protein B10"
FT /id="PRO_0000371291"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 14..201
FT /note="Reticulon"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00170"
FT VAR_SEQ 122..160
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14993207"
FT /id="VSP_037007"
SQ SEQUENCE 201 AA; 23483 MW; 5FD7261418F3F840 CRC64;
MEESVHQSIR FGSVADLIMW KNRRGGFLLL GSTTLLWFLF EKCGYSFFPF VVNTQLLSVV
ILFLWAKSAI LFNRPMPQLP NLEITEEFVF MVADAIRVWI NTVLAVAREI YVGRNAKQLF
RVSVVLWTVS FVGNFLNFLT ILYLGVVLSL LIPFLYERYQ DLIDEKLSLT HRVIQTQYRK
IDERLLQKII AKPTNKIKKM Q
