RTNLM_ARATH
ID RTNLM_ARATH Reviewed; 206 AA.
AC O64837;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Reticulon-like protein B13;
DE Short=AtRTNLB13;
GN Name=RTNLB13; OrderedLocusNames=At2g23640; ORFNames=F26B6.29, F27L4.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-206.
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17604024; DOI=10.1016/j.febslet.2007.06.032;
RA Nziengui H., Bouhidel K., Pillon D., Der C., Marty F., Schoefs B.;
RT "Reticulon-like proteins in Arabidopsis thaliana: structural organization
RT and ER localization.";
RL FEBS Lett. 581:3356-3362(2007).
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=17980018; DOI=10.1111/j.1600-0854.2007.00670.x;
RA Tolley N., Sparkes I.A., Hunter P.R., Craddock C.P., Nuttall J.,
RA Roberts L.M., Hawes C., Pedrazzini E., Frigerio L.;
RT "Overexpression of a plant reticulon remodels the lumen of the cortical
RT endoplasmic reticulum but does not perturb protein transport.";
RL Traffic 9:94-102(2008).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:17980018}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:17980018}.
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DR EMBL; AC003040; AAM14868.1; -; Genomic_DNA.
DR EMBL; AC004482; AAC17096.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07475.1; -; Genomic_DNA.
DR EMBL; BX822075; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T01153; T01153.
DR RefSeq; NP_565555.1; NM_127928.3.
DR AlphaFoldDB; O64837; -.
DR SMR; O64837; -.
DR BioGRID; 2248; 3.
DR STRING; 3702.AT2G23640.1; -.
DR TCDB; 8.A.102.1.7; the reticulon (reticulon) family.
DR PaxDb; O64837; -.
DR PRIDE; O64837; -.
DR ProteomicsDB; 228069; -.
DR EnsemblPlants; AT2G23640.1; AT2G23640.1; AT2G23640.
DR GeneID; 816896; -.
DR Gramene; AT2G23640.1; AT2G23640.1; AT2G23640.
DR KEGG; ath:AT2G23640; -.
DR Araport; AT2G23640; -.
DR TAIR; locus:2046783; AT2G23640.
DR eggNOG; KOG1792; Eukaryota.
DR HOGENOM; CLU_066344_2_1_1; -.
DR InParanoid; O64837; -.
DR OMA; WMFRVGA; -.
DR OrthoDB; 1106300at2759; -.
DR PhylomeDB; O64837; -.
DR PRO; PR:O64837; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64837; baseline and differential.
DR Genevisible; O64837; AT.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR.
DR GO; GO:0071782; C:endoplasmic reticulum tubular network; IDA:UniProtKB.
DR GO; GO:0071458; C:integral component of cytoplasmic side of endoplasmic reticulum membrane; IDA:UniProtKB.
DR GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR GO; GO:0009617; P:response to bacterium; IEA:InterPro.
DR InterPro; IPR003388; Reticulon.
DR InterPro; IPR045064; Reticulon-like_plant.
DR PANTHER; PTHR10994; PTHR10994; 1.
DR Pfam; PF02453; Reticulon; 1.
DR PROSITE; PS50845; RETICULON; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..206
FT /note="Reticulon-like protein B13"
FT /id="PRO_0000371294"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 16..206
FT /note="Reticulon"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00170"
FT CONFLICT 117
FT /note="E -> K (in Ref. 3)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 206 AA; 23771 MW; 47EA50B66703EE63 CRC64;
MANDVTKDPT PKSDIVEDIY LWRRKKLAFS TLLVSTSTWI LLSFYGFTTI TIVSWIGIAV
VSMIFLWGSL LRLLSKVEPE LSGLEVSEEF VVETVRSCRM LMEEMVRWMF RVGAESEWFV
FARTVLGFWI LSRIGNLLDF HTCLFIGLVM GLTVPKLWEE YGDQIQKHLG SLKDKSKGAY
NTTHEKILEM KNKLHHGTEE KVKKSE
