RTNLS_ARATH
ID RTNLS_ARATH Reviewed; 487 AA.
AC Q56X72; Q9FJL6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Reticulon-like protein B21;
DE Short=AtRTNLB21;
GN Name=RTNLB21; OrderedLocusNames=At5g58000; ORFNames=MTI20.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17604024; DOI=10.1016/j.febslet.2007.06.032;
RA Nziengui H., Bouhidel K., Pillon D., Der C., Marty F., Schoefs B.;
RT "Reticulon-like proteins in Arabidopsis thaliana: structural organization
RT and ER localization.";
RL FEBS Lett. 581:3356-3362(2007).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08870.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At5g58000 and At5g58003.; Evidence={ECO:0000305};
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DR EMBL; AB013396; BAB08870.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96983.1; -; Genomic_DNA.
DR EMBL; AK221805; BAD93974.1; -; mRNA.
DR RefSeq; NP_200608.3; NM_125185.3.
DR AlphaFoldDB; Q56X72; -.
DR STRING; 3702.AT5G58000.1; -.
DR iPTMnet; Q56X72; -.
DR PaxDb; Q56X72; -.
DR PRIDE; Q56X72; -.
DR EnsemblPlants; AT5G58000.1; AT5G58000.1; AT5G58000.
DR GeneID; 835911; -.
DR Gramene; AT5G58000.1; AT5G58000.1; AT5G58000.
DR KEGG; ath:AT5G58000; -.
DR Araport; AT5G58000; -.
DR TAIR; locus:2174418; AT5G58000.
DR eggNOG; ENOG502QQKT; Eukaryota.
DR HOGENOM; CLU_020845_1_0_1; -.
DR InParanoid; Q56X72; -.
DR OMA; KYSQSHN; -.
DR PRO; PR:Q56X72; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q56X72; baseline and differential.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR003388; Reticulon.
DR InterPro; IPR044647; RTNLB17/18/21.
DR PANTHER; PTHR46626; PTHR46626; 1.
DR Pfam; PF02453; Reticulon; 1.
DR PROSITE; PS50845; RETICULON; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..487
FT /note="Reticulon-like protein B21"
FT /id="PRO_0000371300"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 230..419
FT /note="Reticulon"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00170"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..142
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..462
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 455
FT /note="E -> G (in Ref. 3; BAD93974)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 487 AA; 55195 MW; 4E6FB4119A09C68A CRC64;
MTPRRSLSSS DSNDKSPSVS VVAKKARSES VEGIEKKTTP GRVKKIRSEV CTTIVKAGEF
DSVALRKVNS LPSPNSEKSD TKTEQEVTII ENSKIPEEVK EFGVCQEMIV SAKSNENEQI
DNGDQEIGDQ DDYEEDGDEE EEREVEKKSV DVKEINVAKE NRVGGVEIKK FSQFQNRTSP
SPSSVRKISP PVIKRATSVY SAPPNSTSST DRFAEQEDNF THSQSKLQSL VDLVMWRDVS
RSTLVFGFGT FLIISSSYAN DLNFSFISVV AYMGLIYLGL MFVLKSLIHR GMVEEERHKV
VGVREEDVKR MLRLIMPYLN ESLHQLRALF SGDPSTTLKM GVVLFVLARC GSSITLWNLA
KFGFLGAFTI PKIFISYSTH FSAYGNFWMR RFRDAWESCN HKKAVALALF TLVWNLSSVT
ARVWAAFMLL VAFRYYQHKM IWTTDQADDD EDDNEEEEAE EEKEQVPPKH KRAPPHMMMP
NKLKKIS
