ID   BCRH_RICBR              Reviewed;         404 AA.
AC   Q1RI77;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Uncharacterized transporter RBE_0856;
GN   OrderedLocusNames=RBE_0856;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RML369-C;
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae in
RT   gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Bcr/CmlA
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000087; ABE04937.1; -; Genomic_DNA.
DR   RefSeq; WP_011477522.1; NC_007940.1.
DR   AlphaFoldDB; Q1RI77; -.
DR   SMR; Q1RI77; -.
DR   STRING; 336407.RBE_0856; -.
DR   EnsemblBacteria; ABE04937; ABE04937; RBE_0856.
DR   KEGG; rbe:RBE_0856; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_001265_47_1_5; -.
DR   OMA; MMFPQIV; -.
DR   OrthoDB; 1452500at2; -.
DR   Proteomes; UP000001951; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   InterPro; IPR004812; Efflux_drug-R_Bcr/CmlA.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00710; efflux_Bcr_CflA; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..404
FT                   /note="Uncharacterized transporter RBE_0856"
FT                   /id="PRO_0000281081"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   404 AA;  44841 MW;  7D411BA3B178DEAC CRC64;
     MKIIAKIPAW MLLCLFTLSP ITETIYTSGL PSITEYFNTD GSTTQITSSL YYLGFALGIL
     TLGRLSDIYG RRPVVLFGLC IYAISSIISI FAPNIETLML ARFVQAFGVS VGSVIGQAMA
     RDSYQGSELS YVYASLSPWL LFIPSLGSSI GGYIIEYSSW HYTFVFFSLT GTVLLTLYCK
     ILPETNPYIN FSQTSKYFEV LKVVIRDKSL WLYAFIIGAF NGIYYGFYIE APFIFIDKMK
     VAPSFYGKLA FLLSFAGIFG GFLGGYLIKK RHIHDQKVMI LGLVFSVIGC SLLAIDALIL
     QDKEVGQNIA VIMMFAPMML HMVGHNLLIP MTLRYALEDY AKVTGTAGSV FGAIYYVLIA
     AVTFLVSKLH SDTIGNFALL FLVLSVSSAA AFYYILILYK KKLT