ID   RU2A_ARATH              Reviewed;         249 AA.
AC   P43333; O04497;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2001, sequence version 2.
DT   25-MAY-2022, entry version 146.
DE   RecName: Full=U2 small nuclear ribonucleoprotein A';
DE            Short=U2 snRNP A';
GN   OrderedLocusNames=At1g09760; ORFNames=F21M12.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. C24; TISSUE=Flower bud;
RA   Yu D.Y., Quigley F., Mache R.;
RL   Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-110.
RC   STRAIN=cv. C24; TISSUE=Flower bud;
RX   PubMed=8281187; DOI=10.1046/j.1365-313x.1993.04061051.x;
RA   Hoefte H., Desprez T., Amselem J., Chiapello H., Rouze P., Caboche M.,
RA   Moisan A., Jourjon M.-F., Charpenteau J.-L., Berthomieu P., Guerrier D.,
RA   Giraudat J., Quigley F., Thomas F., Yu D.-Y., Mache R., Raynal M.,
RA   Cooke R., Grellet F., Delseny M., Parmentier Y., de Marcillac G., Gigot C.,
RA   Fleck J., Philipps G., Axelos M., Bardet C., Tremousaygue D., Lescure B.;
RT   "An inventory of 1152 expressed sequence tags obtained by partial
RT   sequencing of cDNAs from Arabidopsis thaliana.";
RL   Plant J. 4:1051-1061(1993).
CC   -!- FUNCTION: This protein is associated with sn-RNP U2. It helps the A'
CC       protein to bind stem loop IV of U2 snRNA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the U2 small nuclear ribonucleoprotein A family.
CC       {ECO:0000305}.
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DR   EMBL; X69137; CAA48890.1; -; mRNA.
DR   EMBL; AC000132; AAB60746.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE28489.1; -; Genomic_DNA.
DR   EMBL; AY059902; AAL24384.1; -; mRNA.
DR   EMBL; BT000143; AAN15462.1; -; mRNA.
DR   EMBL; Z18200; CAA79133.1; -; mRNA.
DR   PIR; E86231; E86231.
DR   PIR; S30580; S30580.
DR   RefSeq; NP_172447.1; NM_100848.4.
DR   AlphaFoldDB; P43333; -.
DR   SMR; P43333; -.
DR   BioGRID; 22746; 9.
DR   IntAct; P43333; 4.
DR   MINT; P43333; -.
DR   STRING; 3702.AT1G09760.1; -.
DR   iPTMnet; P43333; -.
DR   PaxDb; P43333; -.
DR   PRIDE; P43333; -.
DR   ProteomicsDB; 226657; -.
DR   EnsemblPlants; AT1G09760.1; AT1G09760.1; AT1G09760.
DR   GeneID; 837505; -.
DR   Gramene; AT1G09760.1; AT1G09760.1; AT1G09760.
DR   KEGG; ath:AT1G09760; -.
DR   Araport; AT1G09760; -.
DR   TAIR; locus:2024316; AT1G09760.
DR   eggNOG; KOG1644; Eukaryota.
DR   HOGENOM; CLU_061027_0_1_1; -.
DR   OMA; PNYREYM; -.
DR   OrthoDB; 1447031at2759; -.
DR   PhylomeDB; P43333; -.
DR   PRO; PR:P43333; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; P43333; baseline and differential.
DR   Genevisible; P43333; AT.
DR   GO; GO:0015030; C:Cajal body; IDA:TAIR.
DR   GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR   GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR   GO; GO:0005654; C:nucleoplasm; IDA:TAIR.
DR   GO; GO:0005634; C:nucleus; HDA:TAIR.
DR   GO; GO:0030620; F:U2 snRNA binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:TAIR.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR044640; RU2A.
DR   InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR   PANTHER; PTHR10552; PTHR10552; 1.
DR   SMART; SM00446; LRRcap; 1.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Nucleus; Reference proteome; Repeat;
KW   Ribonucleoprotein; RNA-binding.
FT   CHAIN           1..249
FT                   /note="U2 small nuclear ribonucleoprotein A'"
FT                   /id="PRO_0000074178"
FT   REPEAT          20..41
FT                   /note="LRR 1"
FT   REPEAT          43..64
FT                   /note="LRR 2"
FT   REPEAT          65..87
FT                   /note="LRR 3"
FT   REPEAT          89..110
FT                   /note="LRR 4"
FT   DOMAIN          123..161
FT                   /note="LRRCT"
FT   CONFLICT        107
FT                   /note="D -> H (in Ref. 1 and 5)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        129
FT                   /note="A -> P (in Ref. 1; CAA48890)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   249 AA;  28041 MW;  FE51CBB18FD86DD2 CRC64;
     MVKLTADLIW KSPHFFNAIK ERELDLRGNK IPVIENLGAT EDQFDTIDLS DNEIVKLENF
     PYLNRLGTLL INNNRITRIN PNLGEFLPKL HSLVLTNNRL VNLVEIDPLA SIPKLQYLSL
     LDNNITKKAN YRLYVIHKLK SLRVLDFIKI KAKERAEAAS LFSSKEAEEE VKKVSREEVK
     KVSETAENPE TPKVVAPTAE QILAIKAAII NSQTIEEIAR LEQALKFGQV PAGLIIPDPA
     TNDSAPMEE