ID   RU2A_EMENI              Reviewed;         230 AA.
AC   Q5BGW9; C8VUV0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=U2 small nuclear ribonucleoprotein A';
DE            Short=U2 snRNP A';
GN   Name=lea1; ORFNames=AN0211;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the U2 small nuclear ribonucleoprotein A family.
CC       {ECO:0000305}.
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DR   EMBL; AACD01000005; EAA66084.1; -; Genomic_DNA.
DR   EMBL; BN001308; CBF89966.1; -; Genomic_DNA.
DR   RefSeq; XP_657815.1; XM_652723.1.
DR   AlphaFoldDB; Q5BGW9; -.
DR   SMR; Q5BGW9; -.
DR   STRING; 162425.CADANIAP00002521; -.
DR   EnsemblFungi; CBF89966; CBF89966; ANIA_00211.
DR   EnsemblFungi; EAA66084; EAA66084; AN0211.2.
DR   GeneID; 2875987; -.
DR   KEGG; ani:AN0211.2; -.
DR   eggNOG; KOG1644; Eukaryota.
DR   HOGENOM; CLU_061027_1_0_1; -.
DR   InParanoid; Q5BGW9; -.
DR   OMA; PNYREYM; -.
DR   OrthoDB; 1447031at2759; -.
DR   Proteomes; UP000000560; Chromosome VIII.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR044640; RU2A.
DR   PANTHER; PTHR10552; PTHR10552; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   3: Inferred from homology;
KW   Leucine-rich repeat; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Repeat; Spliceosome.
FT   CHAIN           1..230
FT                   /note="U2 small nuclear ribonucleoprotein A'"
FT                   /id="PRO_0000074184"
FT   REPEAT          19..40
FT                   /note="LRR 1"
FT   REPEAT          41..62
FT                   /note="LRR 2"
FT   REPEAT          65..86
FT                   /note="LRR 3"
FT   DOMAIN          99..137
FT                   /note="LRRCT"
FT   REGION          211..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   230 AA;  26080 MW;  549CF54681DCAE38 CRC64;
     MRLTVELIQN SLSYINPLKD RELDLRDNDI SSLGNFPFFP RLRMLLLARN RVRQIQPSLA
     NSIPGLTTLV LTANNIAELA DLDPLRNLTK LTHLVLLENP VTRKEYYRLW IIWRIPSVRF
     LDYQKVKDAE RAKAAELFGT ATEPTALASK ILGVKSRTFD IPSGGAADQP PPEKRLRVKL
     TDSERKRIEK MIREAKSLQE ITRLERELNE GRIPGGALDG AGNDGDQMQL