ID   RU2A_USTMA              Reviewed;         246 AA.
AC   Q4P5F9; A0A0D1CLI3;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=U2 small nuclear ribonucleoprotein A';
DE            Short=U2 snRNP A';
GN   Name=LEA1; ORFNames=UMAG_04654;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the U2 small nuclear ribonucleoprotein A family.
CC       {ECO:0000305}.
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DR   EMBL; CM003152; KIS67558.1; -; Genomic_DNA.
DR   RefSeq; XP_011390931.1; XM_011392629.1.
DR   AlphaFoldDB; Q4P5F9; -.
DR   SMR; Q4P5F9; -.
DR   STRING; 5270.UM04654P0; -.
DR   EnsemblFungi; KIS67558; KIS67558; UMAG_04654.
DR   GeneID; 23564763; -.
DR   KEGG; uma:UMAG_04654; -.
DR   VEuPathDB; FungiDB:UMAG_04654; -.
DR   eggNOG; KOG1644; Eukaryota.
DR   HOGENOM; CLU_061027_1_0_1; -.
DR   InParanoid; Q4P5F9; -.
DR   OMA; PNYREYM; -.
DR   OrthoDB; 1447031at2759; -.
DR   Proteomes; UP000000561; Chromosome 13.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR044640; RU2A.
DR   InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR   PANTHER; PTHR10552; PTHR10552; 1.
DR   SMART; SM00369; LRR_TYP; 2.
DR   SMART; SM00446; LRRcap; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   3: Inferred from homology;
KW   Leucine-rich repeat; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Repeat; Spliceosome.
FT   CHAIN           1..246
FT                   /note="U2 small nuclear ribonucleoprotein A'"
FT                   /id="PRO_0000074187"
FT   REPEAT          19..40
FT                   /note="LRR 1"
FT   REPEAT          42..63
FT                   /note="LRR 2"
FT   REPEAT          64..85
FT                   /note="LRR 3"
FT   REPEAT          88..109
FT                   /note="LRR 4"
FT   DOMAIN          122..160
FT                   /note="LRRCT"
SQ   SEQUENCE   246 AA;  27919 MW;  45ACF6DFB6A1D403 CRC64;
     MKLTPELLSR SSSSINTLRD RELDLRGLKI PAIENLGVTR DQNDAIDLTD NDIRYLGNFP
     LLQQLKTLQL ANNLISRIDP RIGHSLPALH SLNLTNNCIS DLSELVHLSK CRRLEYLCLM
     GTPASREAQY REFVIWKLPQ VRVLDYQRIK DKERARAKDL METEDGRPTA LAANILKKLG
     ASAMDVDVDV MVGKQKTFEP GRLNGSSRRL LTAEERKAIE DAIESSESLE EIRKLEEQLK
     MGHTFV