RU2B_ORYSI
ID RU2B_ORYSI Reviewed; 232 AA.
AC B8AM21;
DT 18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=U2 small nuclear ribonucleoprotein B'';
DE Short=U2 snRNP B'';
GN ORFNames=OsI_11177;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Involved in nuclear pre-mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Component of the spliceosome where it is associated with snRNP
CC U2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, Cajal body
CC {ECO:0000250|UniProtKB:O22922}. Nucleus, nucleoplasm
CC {ECO:0000250|UniProtKB:O22922}. Cytoplasm
CC {ECO:0000250|UniProtKB:O22922}. Note=Present in coiled bodies and an
CC interchromatin network. Redistributed throughout the cytoplasm upon
CC entry into mitosis. Also detected in central nucleolar vacuole.
CC {ECO:0000250|UniProtKB:O22922}.
CC -!- SIMILARITY: Belongs to the RRM U1 A/B'' family. {ECO:0000305}.
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DR EMBL; CM000128; EEC75061.1; -; Genomic_DNA.
DR AlphaFoldDB; B8AM21; -.
DR SMR; B8AM21; -.
DR STRING; 39946.B8AM21; -.
DR EnsemblPlants; BGIOSGA010914-TA; BGIOSGA010914-PA; BGIOSGA010914.
DR Gramene; BGIOSGA010914-TA; BGIOSGA010914-PA; BGIOSGA010914.
DR HOGENOM; CLU_041869_1_1_1; -.
DR OMA; NQTIYVN; -.
DR Proteomes; UP000007015; Chromosome 3.
DR GO; GO:0015030; C:Cajal body; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005686; C:U2 snRNP; ISS:UniProtKB.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Repeat; Ribonucleoprotein; RNA-binding; Spliceosome.
FT CHAIN 1..232
FT /note="U2 small nuclear ribonucleoprotein B''"
FT /id="PRO_0000416932"
FT DOMAIN 10..89
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 158..232
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 92..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 26073 MW; 55CB92CEA279ED4A CRC64;
MLSGDIPPNQ TVYLRNLNEK VKKEELKRSL YALCSQYGRI LDVVALKTPK LRGQAWVVFS
EITAATNAFR GLQEFDFYGK RMRVQYAKTK SDCLATEDGS TAPKEKRKKQ EEKAAEKKRR
AEEAQQSGPN AAAQSNGTGY QASRLGKTSQ EPPAPPNNIL FIQNLPAETT SMMLQILFQQ
YPGFREVRMI EAKPGIAFVE YEDDSQSMVA MQALQGFKIT PYNPMAISYA KK
