RUBR2_DESDA
ID RUBR2_DESDA Reviewed; 62 AA.
AC Q93PP8; B8J0L1;
DT 23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Rubredoxin-2;
DE Short=Rd-2;
GN Name=rd2; OrderedLocusNames=Ddes_1386;
OS Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfovibrio.
OX NCBI_TaxID=525146;
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11454214; DOI=10.1046/j.1365-2958.2001.02509.x;
RA da Costa P.N., Romao C.V., LeGall J., Xavier A.V., Melo E., Teixeira M.,
RA Saraiva L.M.;
RT "The genetic organization of Desulfovibrio desulphuricans ATCC 27774
RT bacterioferritin and rubredoxin-2 genes: involvement of rubredoxin in iron
RT metabolism.";
RL Mol. Microbiol. 41:217-227(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27774 / DSM 6949 / MB;
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T.,
RA Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Ovchinnikova G., Hazen T.C.;
RT "Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str.
RT ATCC 27774.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000305}
RP PROTEIN SEQUENCE OF 2-40, COFACTOR, SUBUNIT, REDOX POTENTIOMETRY,
RP ABSORPTION SPECTROSCOPY, AND EPR SPECTROSCOPY.
RX PubMed=9662435; DOI=10.1016/s0014-5793(98)00610-3;
RA LeGall J., Liu M.Y., Gomes C.M., Braga V., Pacheco I., Regalla M.,
RA Xavier A.V., Teixeira M.;
RT "Characterisation of a new rubredoxin isolated from Desulfovibrio
RT desulfuricans 27774: definition of a new family of rubredoxins.";
RL FEBS Lett. 429:295-298(1998).
CC -!- FUNCTION: Rubredoxin is a small nonheme, iron protein lacking acid-
CC labile sulfide. Its single Fe, chelated to 4 Cys, functions as an
CC electron acceptor and may also stabilize the conformation of the
CC molecule.
CC -!- COFACTOR:
CC Name=Fe(3+); Xref=ChEBI:CHEBI:29034;
CC Evidence={ECO:0000269|PubMed:9662435};
CC Note=Binds 1 Fe(3+) ion per subunit. {ECO:0000269|PubMed:9662435};
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:9662435}.
CC -!- MISCELLANEOUS: The midpoint reduction potential is 25 mV.
CC {ECO:0000269|PubMed:9662435}.
CC -!- SIMILARITY: Belongs to the rubredoxin family. {ECO:0000305}.
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DR EMBL; AF321851; AAK60121.1; -; Genomic_DNA.
DR EMBL; CP001358; ACL49288.1; -; Genomic_DNA.
DR RefSeq; WP_012625012.1; NC_011883.1.
DR AlphaFoldDB; Q93PP8; -.
DR SMR; Q93PP8; -.
DR STRING; 525146.Ddes_1386; -.
DR EnsemblBacteria; ACL49288; ACL49288; Ddes_1386.
DR KEGG; dds:Ddes_1386; -.
DR eggNOG; COG1773; Bacteria.
DR HOGENOM; CLU_128747_3_2_7; -.
DR OMA; CGAGKKM; -.
DR OrthoDB; 2047418at2; -.
DR GO; GO:0009055; F:electron transfer activity; NAS:UniProtKB.
DR GO; GO:0008199; F:ferric iron binding; IDA:UniProtKB.
DR GO; GO:0022900; P:electron transport chain; IDA:UniProtKB.
DR CDD; cd00730; rubredoxin; 1.
DR InterPro; IPR024922; Rubredoxin.
DR InterPro; IPR024934; Rubredoxin-like_dom.
DR InterPro; IPR024935; Rubredoxin_dom.
DR InterPro; IPR018527; Rubredoxin_Fe_BS.
DR Pfam; PF00301; Rubredoxin; 1.
DR PIRSF; PIRSF000071; Rubredoxin; 1.
DR PRINTS; PR00163; RUBREDOXIN.
DR PROSITE; PS00202; RUBREDOXIN; 1.
DR PROSITE; PS50903; RUBREDOXIN_LIKE; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Electron transport; Iron; Metal-binding;
KW Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:9662435"
FT CHAIN 2..62
FT /note="Rubredoxin-2"
FT /id="PRO_0000135036"
FT DOMAIN 7..58
FT /note="Rubredoxin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00241"
FT BINDING 10
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00241"
FT BINDING 15
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00241"
FT BINDING 45
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00241"
FT BINDING 48
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00241"
SQ SEQUENCE 62 AA; 7197 MW; 2843E5BF2178B736 CRC64;
MAEPQDMWRC QMVNCGYVYD PDRGDKRRKV PAGTKFEDLP EDWRCPVCGA GKKSFRRLSD
EA
