ID   RUN3B_MOUSE             Reviewed;         408 AA.
AC   Q6PDC0; Q6PFX5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=RUN domain-containing protein 3B;
GN   Name=Rundc3b; Synonyms=Gm440;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain, and Eye;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216 AND SER-217, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3]
RP   METHYLATION [LARGE SCALE ANALYSIS] AT ARG-13, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain;
RX   PubMed=24129315; DOI=10.1074/mcp.o113.027870;
RA   Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA   Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA   Bedford M.T., Comb M.J.;
RT   "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT   methylation.";
RL   Mol. Cell. Proteomics 13:372-387(2014).
CC   -!- SUBUNIT: Interacts with RAP2A. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RUNDC3 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC057375; AAH57375.1; -; mRNA.
DR   EMBL; BC058808; AAH58808.1; -; mRNA.
DR   CCDS; CCDS19083.1; -.
DR   RefSeq; NP_941022.1; NM_198620.1.
DR   AlphaFoldDB; Q6PDC0; -.
DR   SMR; Q6PDC0; -.
DR   STRING; 10090.ENSMUSP00000040108; -.
DR   iPTMnet; Q6PDC0; -.
DR   PhosphoSitePlus; Q6PDC0; -.
DR   EPD; Q6PDC0; -.
DR   MaxQB; Q6PDC0; -.
DR   PaxDb; Q6PDC0; -.
DR   PRIDE; Q6PDC0; -.
DR   ProteomicsDB; 256813; -.
DR   Antibodypedia; 45244; 57 antibodies from 16 providers.
DR   DNASU; 242819; -.
DR   Ensembl; ENSMUST00000047485; ENSMUSP00000040108; ENSMUSG00000040570.
DR   GeneID; 242819; -.
DR   KEGG; mmu:242819; -.
DR   UCSC; uc008wkk.1; mouse.
DR   CTD; 154661; -.
DR   MGI; MGI:2685286; Rundc3b.
DR   VEuPathDB; HostDB:ENSMUSG00000040570; -.
DR   eggNOG; KOG4381; Eukaryota.
DR   GeneTree; ENSGT00940000159175; -.
DR   HOGENOM; CLU_045987_0_0_1; -.
DR   InParanoid; Q6PDC0; -.
DR   PhylomeDB; Q6PDC0; -.
DR   TreeFam; TF323904; -.
DR   BioGRID-ORCS; 242819; 3 hits in 71 CRISPR screens.
DR   PRO; PR:Q6PDC0; -.
DR   Proteomes; UP000000589; Chromosome 5.
DR   RNAct; Q6PDC0; protein.
DR   Bgee; ENSMUSG00000040570; Expressed in trigeminal ganglion and 172 other tissues.
DR   ExpressionAtlas; Q6PDC0; baseline and differential.
DR   Genevisible; Q6PDC0; MM.
DR   Gene3D; 1.20.58.900; -; 1.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF140741; SSF140741; 1.
DR   PROSITE; PS50826; RUN; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Methylation; Phosphoprotein; Reference proteome.
FT   CHAIN           1..408
FT                   /note="RUN domain-containing protein 3B"
FT                   /id="PRO_0000336051"
FT   DOMAIN          58..190
FT                   /note="RUN"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00178"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          213..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          301..326
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        337..352
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         13
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0007744|PubMed:24129315"
FT   MOD_RES         216
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
FT   MOD_RES         217
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
SQ   SEQUENCE   408 AA;  45138 MW;  035E82D9EACDCD8E CRC64;
     MASRSLGGLS GSRGGGGGGG GKKSLSARNA AVERRNLITV CRFSVKTLID RSCFETIDDS
     SPEFNNFAAV LEQILSHRLK GQVTWFGYES PRSFWDYIRV ACRKVSQNCI CSIENMENVS
     SSRAKGRAWI RVALMEKHLS EYISTALRDF KTTRRFYEDG AIVLGEEANM LAGMLLGLNA
     IDFSFCLKGE GLDGTFPAVI DYTPYLKFEQ SSDSISSDEE ELRTFGSSDS ESSTPENVGP
     PLILDENTWF NKCKRVRQKY QLTLEQKGYL EELLRLRENQ LSESVSQNKI LLQRIEDSDL
     AHKLEKEQLE YIIVELQDQL KSYQSLDQLS AEVSLSQASL DPSHSQEGDG KQDSLNFIGE
     GKEDTPSLLG LCGSLTSVAS YKSLTSLKSN DCLASPTTEL TSPGLTPS