ID   RUSD1_BOVIN             Reviewed;         308 AA.
AC   Q17QT4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 1;
GN   Name=RPUSD1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hippocampus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC       {ECO:0000305}.
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DR   EMBL; BC118196; AAI18197.1; -; mRNA.
DR   RefSeq; NP_001069342.1; NM_001075874.1.
DR   RefSeq; XP_010817400.1; XM_010819098.2.
DR   AlphaFoldDB; Q17QT4; -.
DR   SMR; Q17QT4; -.
DR   STRING; 9913.ENSBTAP00000000204; -.
DR   PaxDb; Q17QT4; -.
DR   Ensembl; ENSBTAT00000000204; ENSBTAP00000000204; ENSBTAG00000000179.
DR   Ensembl; ENSBTAT00000084979; ENSBTAP00000067589; ENSBTAG00000000179.
DR   GeneID; 525521; -.
DR   KEGG; bta:525521; -.
DR   CTD; 113000; -.
DR   VEuPathDB; HostDB:ENSBTAG00000000179; -.
DR   VGNC; VGNC:34154; RPUSD1.
DR   eggNOG; KOG1919; Eukaryota.
DR   GeneTree; ENSGT00510000048339; -.
DR   HOGENOM; CLU_016902_10_0_1; -.
DR   InParanoid; Q17QT4; -.
DR   OMA; HVSQSRM; -.
DR   OrthoDB; 821308at2759; -.
DR   TreeFam; TF324755; -.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000000179; Expressed in parenchyma of mammary gland and 104 other tissues.
DR   ExpressionAtlas; Q17QT4; baseline.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IBA:GO_Central.
DR   CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SUPFAM; SSF55120; SSF55120; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Reference proteome.
FT   CHAIN           1..308
FT                   /note="RNA pseudouridylate synthase domain-containing
FT                   protein 1"
FT                   /id="PRO_0000300815"
FT   REGION          257..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        262..289
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        67
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UJJ7"
SQ   SEQUENCE   308 AA;  34177 MW;  DE37A957823B5834 CRC64;
     MEPGSVENLC VVYRSHDFLV VNKHWDVRID SKAWRETLTL QKQLRHRFPE LADPDTYYGF
     RFCHQLDFST SGALCVALNK AAAGSAYRCF KDRRVTKAYL ALVRGHVQES RMTISYAIGK
     NSTEGRTHTM CIEGTQGCEN PKPSLTELVV LEHGLYAGDP VSKVLLQPLT GRTHQLRVHC
     SALGHPIVGD LTYGHALGQE DQPFRMMLHA FYLRIPTSAE CVEACTPDPF VPSLDACWSP
     HTLLQPLDEL VQVLRAAPDP DPSEGGPGPC SPCTPLPGPG RPPPPPETEV QRASCLQWLS
     EWTLEPDN