ID   RUSD1_DANRE             Reviewed;         293 AA.
AC   Q08C69;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 1;
GN   Name=rpusd1; ORFNames=zgc:153465;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC       {ECO:0000305}.
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DR   EMBL; BC124362; AAI24363.1; -; mRNA.
DR   RefSeq; NP_001070221.1; NM_001076753.1.
DR   AlphaFoldDB; Q08C69; -.
DR   SMR; Q08C69; -.
DR   STRING; 7955.ENSDARP00000113540; -.
DR   PaxDb; Q08C69; -.
DR   GeneID; 767786; -.
DR   KEGG; dre:767786; -.
DR   CTD; 113000; -.
DR   ZFIN; ZDB-GENE-060929-444; rpusd1.
DR   eggNOG; KOG1919; Eukaryota.
DR   InParanoid; Q08C69; -.
DR   PhylomeDB; Q08C69; -.
DR   PRO; PR:Q08C69; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IBA:GO_Central.
DR   CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SUPFAM; SSF55120; SSF55120; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..293
FT                   /note="RNA pseudouridylate synthase domain-containing
FT                   protein 1"
FT                   /id="PRO_0000300818"
FT   ACT_SITE        67
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   293 AA;  33340 MW;  4A84CC1E562E2867 CRC64;
     MEPASLENLS VLYQSTNYIV VNKHWDIRID SKMWYEKQTV QSQLKHHFPE LADPGTYYGF
     RFCHQLDFST SGALCVALNK AAAGQAYRCF KDRRVTKAYL ALVRGTVTEE NLSLDFAIGK
     NTTEGKTHMM CTEGTEGCEN PKPCQTEVTV LEYGTYDGDQ VTKVLLQPLT GRTHQLRVHC
     SAIGHPIVGD YTYSLRTDNS PYRMMLHAYF LHIPLHNEPI HVTAPDPFVP SLDAKWAPLR
     CVNILEDLLK NILTKLQAAM QEEAEPEPRT SSPVESEEQR AQCQQWLCEW SLE