ID   RUSF1_DICDI             Reviewed;         527 AA.
AC   Q86K80; Q550A9;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=RUS family member 1;
GN   Name=rusf1; ORFNames=DDB_G0277179;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [3]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16507593; DOI=10.1242/jcs.02819;
RA   Torija P., Vicente J.J., Rodrigues T.B., Robles A., Cerdan S., Sastre L.,
RA   Calvo R.M., Escalante R.;
RT   "Functional genomics in Dictyostelium: midA, a new conserved protein, is
RT   required for mitochondrial function and development.";
RL   J. Cell Sci. 119:1154-1164(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:16507593}.
CC   -!- SIMILARITY: Belongs to the RUS1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL68775.1; -; Genomic_DNA.
DR   RefSeq; XP_642707.1; XM_637615.1.
DR   AlphaFoldDB; Q86K80; -.
DR   STRING; 44689.DDB0232151; -.
DR   PaxDb; Q86K80; -.
DR   EnsemblProtists; EAL68775; EAL68775; DDB_G0277179.
DR   GeneID; 8620899; -.
DR   KEGG; ddi:DDB_G0277179; -.
DR   dictyBase; DDB_G0277179; -.
DR   eggNOG; KOG4249; Eukaryota.
DR   HOGENOM; CLU_517245_0_0_1; -.
DR   InParanoid; Q86K80; -.
DR   OMA; MIESYFY; -.
DR   PhylomeDB; Q86K80; -.
DR   PRO; PR:Q86K80; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006968; RUS_fam.
DR   PANTHER; PTHR12770; PTHR12770; 2.
DR   Pfam; PF04884; UVB_sens_prot; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..527
FT                   /note="RUS family member 1"
FT                   /id="PRO_0000356846"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          350..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        21
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        243
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        346
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        467
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        497
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   527 AA;  59685 MW;  724CEDF5DEC0D76F CRC64;
     MQYNGKSQQS INKINCIIEK NQSNSIINKF QVASPYDDYD DRLNFLETIE KNSGFYNVLC
     ELFLPNGYPD SVTTDYFGYQ FWDSIQALCS TITGTLATRA ILKGYGVGDS SATVASATTQ
     WLIRDGMGMI GRIVFAWRKG TDLDCNSKKW RYTADILNNI GMAFEMISPL FSSQLFLPLS
     CIGLIAKSIC GVAGGCTKAS LTQHFAKRDN LADVSAKDGS QETAVNLVGM LLSVIVSSFI
     NDNTSLIVTW LVFLFFTSLH LFCNYRAVSA VQLKSINRYR AYLIYDYFIH NQGSIPSPSE
     ISKLENILFS IKELDIRVGV SLCNIYKVQQ KQQKLNNQFL QQKLNNITKT KNVNNNNNNN
     NNNNNNNNNN NNNKNNNINN INNNINNNIN NNINNNINNK NNNNNNNNNN NNNNNNNNNN
     NNNNNKNSLE IIKKIKKSKS FIIWKKHSQR GNKILEKDFT LLIALLNGST TRDMIESYFY
     AVEYFHLSSV QIPPTINISG TFFKRLEEKG WDLDRALLNS EGWTFGI