位置:首页 > 蛋白库 > RUSF1_MOUSE
RUSF1_MOUSE
ID   RUSF1_MOUSE             Reviewed;         466 AA.
AC   Q91W34; Q3TCP4; Q3UEA8; Q3UFY1;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=RUS family member 1 {ECO:0000305};
GN   Name=Rusf1 {ECO:0000312|MGI:MGI:2384572};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=C57BL/6J, and NOD; TISSUE=Bone marrow;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=FVB/N; TISSUE=Salivary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brown adipose tissue, Liver, Lung, Pancreas, Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q91W34-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q91W34-2; Sequence=VSP_024257, VSP_024258;
CC   -!- SIMILARITY: Belongs to the RUS1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AK148236; BAE28428.1; -; mRNA.
DR   EMBL; AK149645; BAE29003.1; -; mRNA.
DR   EMBL; AK170611; BAE41911.1; -; mRNA.
DR   EMBL; BC017158; AAH17158.1; -; mRNA.
DR   CCDS; CCDS21895.1; -. [Q91W34-1]
DR   RefSeq; NP_663565.2; NM_145590.2.
DR   AlphaFoldDB; Q91W34; -.
DR   STRING; 10090.ENSMUSP00000033044; -.
DR   iPTMnet; Q91W34; -.
DR   PhosphoSitePlus; Q91W34; -.
DR   SwissPalm; Q91W34; -.
DR   EPD; Q91W34; -.
DR   MaxQB; Q91W34; -.
DR   PaxDb; Q91W34; -.
DR   PeptideAtlas; Q91W34; -.
DR   PRIDE; Q91W34; -.
DR   DNASU; 233913; -.
DR   GeneID; 233913; -.
DR   KEGG; mmu:233913; -.
DR   UCSC; uc009jyv.2; mouse. [Q91W34-1]
DR   CTD; 64755; -.
DR   MGI; MGI:2384572; Rusf1.
DR   eggNOG; KOG4249; Eukaryota.
DR   InParanoid; Q91W34; -.
DR   OrthoDB; 1357597at2759; -.
DR   PhylomeDB; Q91W34; -.
DR   TreeFam; TF326424; -.
DR   BioGRID-ORCS; 233913; 1 hit in 72 CRISPR screens.
DR   PRO; PR:Q91W34; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q91W34; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006968; RUS_fam.
DR   PANTHER; PTHR12770; PTHR12770; 1.
DR   Pfam; PF04884; UVB_sens_prot; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Alternative splicing; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q96GQ5"
FT   CHAIN           2..466
FT                   /note="RUS family member 1"
FT                   /id="PRO_0000282931"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96GQ5"
FT   VAR_SEQ         317..337
FT                   /note="TGFWPSLSLSLGVPLHHLVSS -> IGDPSLWFLVPGFPSLPSPSA (in
FT                   isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:16141072"
FT                   /id="VSP_024257"
FT   VAR_SEQ         338..466
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:16141072"
FT                   /id="VSP_024258"
FT   CONFLICT        41
FT                   /note="G -> C (in Ref. 1; BAE28428)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        147
FT                   /note="L -> F (in Ref. 1; BAE41911/BAE29003/BAE28428)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        364
FT                   /note="Q -> R (in Ref. 1; BAE29003/BAE28428)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        401
FT                   /note="E -> Q (in Ref. 1; BAE29003/BAE28428)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   466 AA;  50469 MW;  B546CEDB8F8E4154 CRC64;
     MADAASLRAP LCTEQFGSGA PRGCSAAADG SLQWDGARRW GWLSRAPIAK PGQHAGGGGG
     PWAALTALSG LRSVLLPQGF PDSVSPDYLP YQLWDSVQAF ASSLSGSLAT QAVLQGLGVG
     NAKASVSAAT STWLVKDSTG MLGRIILAWW KGSKLDCNAK QWRLFADILN DVAMFLEIMA
     PMYPIFFTMT VSTSNLAKCI VGVAGGATRA ALTMHQARRN NMADVSAKDS SQETVVNLAG
     LLVSLLMLPL VSDCPSLSLG CFVLLTALHI YANYRAVRAL VLETLNESRL QLVLEHFLQR
     GEVLEPASAN QMEPLWTGFW PSLSLSLGVP LHHLVSSVSE LKQLVEGHHE PYLLCWNKSR
     NQVQVALSQE AGPETVLRAA THGLILGALQ EDGPLPGELA ELRHQVQADP KKESWILVRE
     THQVLDTLFP KFLKGLQAAG WKTEKHHLEV DEWRATWPLS PEKKVL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024