BCSC_ECO57
ID BCSC_ECO57 Reviewed; 1154 AA.
AC Q8X5M0; Q8X3J4;
DT 26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 3.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Putative cellulose synthase operon protein C;
DE Flags: Precursor;
GN Name=bcsC; OrderedLocusNames=Z4944/Z4945, ECs4410;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Required for maximal bacterial cellulose synthesis.
CC {ECO:0000250}.
CC -!- PATHWAY: Glycan metabolism; bacterial cellulose biosynthesis.
CC -!- SIMILARITY: Belongs to the AcsC/BcsC family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG58671.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAG58671.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AAG58672.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAB37833.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB37833.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AE005174; AAG58672.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AE005174; AAG58671.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BA000007; BAB37833.1; ALT_SEQ; Genomic_DNA.
DR PIR; B91180; B91180.
DR PIR; C86026; C86026.
DR PIR; D86026; D86026.
DR RefSeq; NP_312437.1; NC_002695.1.
DR AlphaFoldDB; Q8X5M0; -.
DR SMR; Q8X5M0; -.
DR STRING; 155864.EDL933_4784; -.
DR EnsemblBacteria; AAG58671; AAG58671; Z4944.
DR EnsemblBacteria; AAG58672; AAG58672; Z4945.
DR KEGG; ece:Z4944; -.
DR KEGG; ece:Z4945; -.
DR PATRIC; fig|386585.9.peg.4610; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG3118; Bacteria.
DR HOGENOM; CLU_001631_2_0_6; -.
DR UniPathway; UPA00694; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR008410; BCSC_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF05420; BCSC_C; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; SSF48452; 4.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 5: Uncertain;
KW Cellulose biosynthesis; Reference proteome; Repeat; Signal; TPR repeat.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..1154
FT /note="Putative cellulose synthase operon protein C"
FT /id="PRO_0000106430"
FT REPEAT 62..95
FT /note="TPR 1"
FT REPEAT 266..299
FT /note="TPR 2"
FT REPEAT 300..333
FT /note="TPR 3"
FT REPEAT 348..381
FT /note="TPR 4"
FT REPEAT 382..415
FT /note="TPR 5"
FT REPEAT 458..491
FT /note="TPR 6"
FT REPEAT 600..633
FT /note="TPR 7"
FT REPEAT 707..741
FT /note="TPR 8"
SQ SEQUENCE 1154 AA; 127462 MW; F7288C6479AAA23C CRC64;
MRKFTLNIFT LSLGLAVMPM VEAAPTAQQQ LLEQVRLGEA THREDLVQQS LYRLELIDPN
NPDVVAARFR SLLRQGDIDG AQKQLDRLSQ LAPSSNAYKS SRTTMLLSTP DGRQALQQAR
LQATTGHAEE AVANLFNGAP PEGDIAVEYW STVAKIPARR GEAINQLKRI NADEPGNTGL
QNNLALLLFS SDRRDEGFAV LEQMAKSNAG REGASKIWYG QIKDMPVSDA SVSALKKYLS
IFSDGDSVAA AQSQLAEQQK QLADPAFRAR AQGLAAVDSG MAGKAIPELQ QAVRANPKDS
EALGALGQAY SQKGDRANAV ANLEKALALD PHSSNNDKWN SLLKVNRYWL AIQQGDAALK
ANNPDRAERL FQQARNVDNT DSYAVLGLGD VAMARKDYPA AERYYQQTLR MDSGNTNAVR
GLANIYRQQS PEKAEAFIAS LSASQRRSID DIERSLQNDR LAQQAEALEN QGKWAQAAAL
QRQRLALDPG SVWITYRLSQ DLWQAGQRSQ ADTLMRNLAQ QKPNDPEQVY AYGLYLSGHD
QDRAALAHIN SLPRAQWSSN IQELVNRLQS DQVLETANRL RESGKEAEAE AMLRQQPPST
RIDLTLADWA LQRRDYTAAR AAYQNVLTRE PTNADAILGL TEVDIAAGDT AAARSQLAKL
PATDNASLNT QRRVALAQAQ LGDTAAAQQT FNKLIPQAKS QPPSMESAMV LRDGAKFEAQ
AGDPKQALET YKDAMVASGV TTTRPQDNDT FTRLTRNDEK DDWLKRGVRS DAADLYRQQD
LNVTLEHDYW GSSGTGGYSD LKAHTTMLQV DAPYSDGRMF FRSDFVNMNV GSFSTNADGK
WDDNWGTCTL RDCSGNRSQS DSGASVAVGW RNDVWSWDIG TTPMGFNVVD VVGGISYSDD
IGPLGYTVNA HRRPISSSLL AFGGQKDFPS NTGKKWGGVR ADGVGLSLSY DKGEANGVWA
SLSGDQLTGK NVEDNWRVRW MTGYYYKVIN QNNRRVTIGL NNMIWHYDKD LSGYSLGQGG
YYSPQEYLSF AIPVMWRERT ENWSWELGAS GSWSHSRTKT MPRYPLMNLI PTDWQEEAAR
QSNDGGSSQG FGYTARALLE RRVTSNWFVG TAIDIQQAKD YAPSHFLLYV RYSAAGWQGD
MDLPPQPLIP YADW
