BCSC_SALTY
ID BCSC_SALTY Reviewed; 1180 AA.
AC Q8ZLB8; Q93IM9;
DT 26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 3.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Cellulose synthase operon protein C;
DE Flags: Precursor;
GN Name=bcsC; OrderedLocusNames=STM3616;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 14028 / SGSG 2980 / CDC 6516-60 / NCTC 12023;
RX PubMed=11260463; DOI=10.1046/j.1365-2958.2001.02337.x;
RA Zogaj X., Nimtz M., Rohde M., Bokranz W., Roemling U.;
RT "The multicellular morphotypes of Salmonella typhimurium and Escherichia
RT coli produce cellulose as the second component of the extracellular
RT matrix.";
RL Mol. Microbiol. 39:1452-1463(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=11929533; DOI=10.1046/j.1365-2958.2002.02802.x;
RA Solano C., Garcia B., Valle J., Berasain C., Ghigo J.-M., Gamazo C.,
RA Lasa I.;
RT "Genetic analysis of Salmonella enteritidis biofilm formation: critical
RT role of cellulose.";
RL Mol. Microbiol. 43:793-808(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Required for maximal bacterial cellulose synthesis.
CC {ECO:0000250}.
CC -!- PATHWAY: Glycan metabolism; bacterial cellulose biosynthesis.
CC -!- SIMILARITY: Belongs to the AcsC/BcsC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC44018.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE006468; AAL22476.1; -; Genomic_DNA.
DR EMBL; AJ315148; CAC86196.1; -; Genomic_DNA.
DR EMBL; AJ315770; CAC44018.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_462517.1; NC_003197.2.
DR RefSeq; WP_001225195.1; NC_003197.2.
DR AlphaFoldDB; Q8ZLB8; -.
DR SMR; Q8ZLB8; -.
DR STRING; 99287.STM3616; -.
DR PaxDb; Q8ZLB8; -.
DR PRIDE; Q8ZLB8; -.
DR EnsemblBacteria; AAL22476; AAL22476; STM3616.
DR GeneID; 1255139; -.
DR KEGG; stm:STM3616; -.
DR PATRIC; fig|99287.12.peg.3822; -.
DR HOGENOM; CLU_001631_2_0_6; -.
DR OMA; ANVEAMP; -.
DR PhylomeDB; Q8ZLB8; -.
DR BioCyc; SENT99287:STM3616-MON; -.
DR UniPathway; UPA00694; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IBA:GO_Central.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 5.
DR InterPro; IPR008410; BCSC_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF05420; BCSC_C; 1.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; SSF48452; 3.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Cellulose biosynthesis; Reference proteome; Repeat; Signal; TPR repeat.
FT SIGNAL 1..45
FT /evidence="ECO:0000255"
FT CHAIN 46..1180
FT /note="Cellulose synthase operon protein C"
FT /id="PRO_0000106431"
FT REPEAT 85..118
FT /note="TPR 1"
FT REPEAT 135..168
FT /note="TPR 2"
FT REPEAT 292..325
FT /note="TPR 3"
FT REPEAT 326..359
FT /note="TPR 4"
FT REPEAT 374..407
FT /note="TPR 5"
FT REPEAT 408..441
FT /note="TPR 6"
FT REPEAT 484..517
FT /note="TPR 7"
FT REPEAT 626..659
FT /note="TPR 8"
FT REPEAT 694..727
FT /note="TPR 9"
FT REPEAT 734..767
FT /note="TPR 10"
SQ SEQUENCE 1180 AA; 129801 MW; 378F94806CC9AA43 CRC64;
MRKFTLSLMH AFLPAGGRNA LPGKRGVSRA LLGLSLGMAL TPLAGAATSA QQQLLEQVRL
GEATHREDLV RQSLYRLELI DPNDPQVIAA RFRYLLRQGD SDGAQKLLDR LAQLAPESTA
YQSSRTAMLL STPQGRQSLQ EARLLATTGH TEQAIASYDK LFKGYPPEGE LAVEYWTTVA
KLPARRHEAI NQLQKINAVS PGNNALQNAL AQLLFASGRR DEGFAVLKQM AKSSTGRSAA
SAIWYQQIKD LPVSDASVKA LQDYLTQFSE GDSVSAARAQ LSEQQKQLAD PAFRARSQGI
AAVNAGEGGK AIAQLQQAVS ARQDDSEAVG ALGQAYSQRG DRARAVAQFE KALAMAPHSS
SRDKWESLLK VNRYWLLIQQ GDAALKANNL AQAERFYQQA RAVDNTDSYA VLGLGDVAMA
RKDNAAAERY YQQTLRMDSG NTNAVRGLAN LYRQQSPQKA AAFIASLSAS QRRSIDDIER
SLENDRLAQQ AETLESEGKW AQAAELHRRR LALDPGSVWV TYRLSRDLWQ AGQHAQADAQ
MRSLAQQKPN DPEQVYAYGL YLSGSDRDRA ALAHLNTLPT SQWNSNIQEL AGRLQSNQVL
ESANRLRDSG KEREAEALLR QQPPSTRIAL TLADWAQQRG DNAAARAAYD AVLAREPGNV
DAMLGRVEID IAQGDNAAAR AQLAALPASQ ITSINMQRRV ALAQLQLGDI TAAARTFNRI
TPQAKAQPPS MESAMVLRDA AAFQAQTGEP QRALETYKDA MVAAAITPVR PQDNDTFTRL
TRNDEKDDWL KRGVRSDAAE LYRQQDLNVT LAHDYWGSSG TGGYSDLKAH TTMLQVDAPW
SDGRAFFRTD MVNMDVGRFS TDADGKYDNN WGTCTLEKCS GHRSQADTGA SVAVGWQNET
WRWDIGTTPM GFNVVDVVGG VSYSDDIGPL GYTLNAHRRP ISSSLLAFGG QKDASSNTGT
KWGGVRANGG GVSLSYDKGE ANGVWASLSG DQLSGKNVED NWRVRWMTGY YYKVINENNR
RVTVGLNNMI WHYDKDLSGY SLGQGGYYSP QEYLSFAVPV MWRQRTENWS WELGGSVSWS
HSRNRTMPRY PLMNLIPADY QEDARDQTNG GGSSQGFGYT ARALIERRVT ANWFVGTAVD
IQQAKDYTPS HLLLYVRYSA AGWQGDMDLP PQPLVPYADW
