ID   BDB_BRECH               Reviewed;         118 AA.
AC   Q44856;
DT   19-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Disulfide bond formation protein;
DE   AltName: Full=Disulfide oxidoreductase;
DE   AltName: Full=Thiol-disulfide oxidoreductase;
DE   Flags: Precursor;
GN   Name=bdb;
OS   Brevibacillus choshinensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=54911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-38, AND
RP   CHARACTERIZATION.
RC   STRAIN=HPD31;
RX   PubMed=7836310; DOI=10.1128/jb.177.3.745-749.1995;
RA   Ishihara T., Tomita H., Hasegawa Y., Tsukagoshi N., Yamagata H., Udaka S.;
RT   "Cloning and characterization of the gene for a protein thiol-disulfide
RT   oxidoreductase in Bacillus brevis.";
RL   J. Bacteriol. 177:745-749(1995).
CC   -!- FUNCTION: Stimulates the oxidation and reduction of disulfide bonds in
CC       vitro.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Is found associated with the cell
CC       lysate, thought to be associated with the cell periphery.
CC   -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
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DR   EMBL; D37936; BAA07155.1; -; Genomic_DNA.
DR   PIR; I39787; I39787.
DR   AlphaFoldDB; Q44856; -.
DR   SMR; Q44856; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Oxidoreductase;
KW   Redox-active center; Secreted; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000269|PubMed:7836310"
FT   CHAIN           28..118
FT                   /note="Disulfide bond formation protein"
FT                   /id="PRO_0000034284"
FT   DOMAIN          28..114
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   DISULFID        42..45
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   118 AA;  13326 MW;  C81E7BD4E6177144 CRC64;
     MRAKWLWMTA VGSLLITVLT AWGWAAASSQ DSKIVYVFSD SCGYCQTFRP TLETVLQEYP
     QTSVERLDIR EERDLKEALR LGAEATPTIF VVRDGTVMDK LEGDVAEAVL RSFFQKKS