ABCG9_DICDI
ID ABCG9_DICDI Reviewed; 1448 AA.
AC Q8T683; Q54BS5;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=ABC transporter G family member 9;
DE AltName: Full=ABC transporter ABCG.9;
GN Name=abcG9; ORFNames=DDB_G0293450;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NOMENCLATURE.
RC STRAIN=AX4;
RX PubMed=12456012; DOI=10.1128/ec.1.4.643-652.2002;
RA Anjard C., Loomis W.F.;
RT "Evolutionary analyses of ABC transporters of Dictyostelium discoideum.";
RL Eukaryot. Cell 1:643-652(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000305}.
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DR EMBL; AF482388; AAL91495.1; -; Genomic_DNA.
DR EMBL; AAFI02000211; EAL60709.1; -; Genomic_DNA.
DR RefSeq; XP_629126.1; XM_629124.1.
DR AlphaFoldDB; Q8T683; -.
DR SMR; Q8T683; -.
DR PaxDb; Q8T683; -.
DR EnsemblProtists; EAL60709; EAL60709; DDB_G0293450.
DR GeneID; 8629234; -.
DR KEGG; ddi:DDB_G0293450; -.
DR dictyBase; DDB_G0293450; abcG9.
DR eggNOG; KOG0065; Eukaryota.
DR HOGENOM; CLU_000604_35_0_1; -.
DR InParanoid; Q8T683; -.
DR OMA; GEMHHWI; -.
DR PhylomeDB; Q8T683; -.
DR PRO; PR:Q8T683; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IGC:dictyBase.
DR GO; GO:0031152; P:aggregation involved in sorocarp development; IBA:GO_Central.
DR GO; GO:0031288; P:sorocarp morphogenesis; IBA:GO_Central.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1448
FT /note="ABC transporter G family member 9"
FT /id="PRO_0000391396"
FT TRANSMEM 494..514
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 530..550
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 579..599
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 604..624
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 634..654
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 663..683
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 748..768
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1157..1177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1191..1211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1233..1253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1272..1292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1299..1319
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1422..1442
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 136..385
FT /note="ABC transporter 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 490..717
FT /note="ABC transmembrane type-2 1"
FT DOMAIN 822..1066
FT /note="ABC transporter 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 1157..1389
FT /note="ABC transmembrane type-2 2"
FT REGION 16..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 858..865
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 1448 AA; 164223 MW; FD4C544C505EA56B CRC64;
MDNNVEYELK EVSIQEGGSN LNINTPSGMS DGDFNSGANS PDIVKSENDF DKLAESLEKE
SKQYFAAQDN ENNAGESEED FKLRRYFENS QRMALSNGSK PKKMSICIRN LTVVGRGADL
SVIADLLTPF NWFISLFKPS TWKIEKTSTF NILNNVTCFN RDGQMLLVLG RPGAGCSTLL
RLISNQRGSY ISVDGDIKYG GIPAKEWERY KGEAIYTPEE DSHHPTLTVR ETLDFALKCK
TIHNRLPDEK KVTFREKISS LLLSMFGIVH QADTIVGNEY IRGLSGGERK RLTITEAMVS
SASITCWDCS TRGLDAASAL DYAKSIRIMS DTLHKTSIAS FYQASDSIYN LFDNVLVLEK
GRCIYFGPVG QAKQYFLDLG FDCEPRKSVP DFLTGVTNPQ ERIIRKGFEG RVPETSADFE
QAWKASELCR EMERQQTEHE KKIEVEQPHL DFIEEVRANK SKTNTKTSVY TTSFPTQVRA
LIVRHSQIIW GDKFSLVSRY LSVIIQSFVY GSVFYNMQTN LSGLFTRGGA IFAAILFNAF
LSEGELFATF YGRRILQKQQ SYAMYRPSAF HIAQVVTDIP LTTVQVFLFS IVVYFMFGLQ
YEAGKFFIFC FTLIGATLAT TNMFRAFGNL SPSLYVSQNV MTGILIFMIS YCGYSIPKNK
MHPWFGWFFW ANPFTYAFKA LMANEFMDLN FSCETEAIPY GTDPTTGAPY DNSVRVCASA
GSRPNTLEVK GSDYLMDALT FKSDDRTLNI FITYLWWVLF IIINMVAVEY LEWTSGGFTT
KTYKKGKAPK LNDAEEERKQ NEIVAKATSE MKDTLKMRGG VFTWENIKYT VPVGKTQKLL
LDDVEGWIKP GQMTALMGSS GAGKTTLLDV LAKRKTLGTV QGKTFLNGKA LEIDFERITG
YVEQMDVHNP GLTVREALRF SAKLRQEPSV SLEEKYDYVE HVLEMMEMKH LGDALVGTLE
TGVGISVEER KRLTIGVELV AKPHILFLDE PTSGLDAQSS YNIVKFIRKL ADAGMPLVCT
IHQPSSVLFE HFDRILLLAK GGKTVYFGDI GERSKTLTSY FERQGVRPCT EFENPAEYIL
EATGAGVHGK TEINWPEVWK QSPELQEVRR ELSSLEASGS SSSSNENGVP REFATSIWYQ
TWEVYKRMNV IYFRDPFYAY GSILQAVMTG IIVGFTFWDL KDSSSDMNQR IFFIFQALLL
GILLIFVVMV QFLVQKEYFK RDYASKFYSW FPFAISIVLV EIPYTIVCGS VFFFCSFWTA
GLFMEGQNGA NFYFWIIFII YLFFCVSFGG AIAAVCNHMF LAMTLVPLLI VFLFLFCGVM
VPPSQIPTFW KGWVYHLNPC RYFMEGIITN VLEHQKVNCS YEDLTKFNNP TTLTCEEYFV
PATGYVTNTT SDNSECGYCI FNSGEQYYKT LEWDASNKGR SIAILIAFWM FNIFLVVSFV
YLTRKPSR
