ID   RUXE_CAEBR              Reviewed;          90 AA.
AC   A8XDT0;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable small nuclear ribonucleoprotein E;
DE            Short=snRNP-E;
DE   AltName: Full=Sm protein E;
DE            Short=Sm-E;
DE            Short=SmE;
GN   Name=snr-6; ORFNames=CBG11756;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Plays a role in pre-mRNA splicing as a core component of the
CC       spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins
CC       (snRNPs), the building blocks of the spliceosome.
CC       {ECO:0000250|UniProtKB:P62304}.
CC   -!- SUBUNIT: Core component of the spliceosomal U1, U2, U4 and U5 small
CC       nuclear ribonucleoproteins (snRNPs), the building blocks of the
CC       spliceosome. {ECO:0000250|UniProtKB:P62304}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P62304}.
CC       Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62304}.
CC   -!- SIMILARITY: Belongs to the snRNP Sm proteins family. {ECO:0000305}.
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DR   EMBL; HE601289; CAP30825.1; -; Genomic_DNA.
DR   RefSeq; XP_002641005.1; XM_002640959.1.
DR   AlphaFoldDB; A8XDT0; -.
DR   SMR; A8XDT0; -.
DR   STRING; 6238.CBG11756; -.
DR   EnsemblMetazoa; CBG11756.1; CBG11756.1; WBGene00032831.
DR   GeneID; 8582999; -.
DR   KEGG; cbr:CBG_11756; -.
DR   CTD; 8582999; -.
DR   WormBase; CBG11756; CBP02878; WBGene00032831; Cbr-snr-6.
DR   eggNOG; KOG1774; Eukaryota.
DR   HOGENOM; CLU_125186_1_0_1; -.
DR   InParanoid; A8XDT0; -.
DR   OMA; TIWLYEQ; -.
DR   OrthoDB; 1594132at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0043186; C:P granule; IEA:EnsemblMetazoa.
DR   GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR   GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0005687; C:U4 snRNP; IBA:GO_Central.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IBA:GO_Central.
DR   CDD; cd01718; Sm_E; 1.
DR   InterPro; IPR001163; LSM_dom_euk/arc.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR027078; snRNP-E.
DR   PANTHER; PTHR11193; PTHR11193; 1.
DR   Pfam; PF01423; LSM; 1.
DR   SMART; SM00651; Sm; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Spliceosome.
FT   CHAIN           1..90
FT                   /note="Probable small nuclear ribonucleoprotein E"
FT                   /id="PRO_0000340652"
SQ   SEQUENCE   90 AA;  10594 MW;  4AC481CCDFFC6468 CRC64;
     MSQRKIQKVM VQPVNLIFRY LQNRTRVQIW LYEDVTHRLE GYIIGFDEFM NVVFDEAEEV
     NMKTKGRNKI GRILLKGDNI TLIHAAAQEA