ID   RUXE_CAEEL              Reviewed;          90 AA.
AC   Q9XTU6;
DT   28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Probable small nuclear ribonucleoprotein E;
DE            Short=snRNP-E;
DE   AltName: Full=Sm protein E;
DE            Short=Sm-E;
DE            Short=SmE;
GN   Name=snr-6; ORFNames=Y49E10.15;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000312|EMBL:CAB11551.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Plays a role in pre-mRNA splicing as a core component of the
CC       spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins
CC       (snRNPs), the building blocks of the spliceosome.
CC       {ECO:0000250|UniProtKB:P62304}.
CC   -!- SUBUNIT: Core component of the spliceosomal U1, U2, U4 and U5 small
CC       nuclear ribonucleoproteins (snRNPs), the building blocks of the
CC       spliceosome. {ECO:0000250|UniProtKB:P62304}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P62304}.
CC       Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62304}.
CC   -!- SIMILARITY: Belongs to the snRNP Sm proteins family. {ECO:0000305}.
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DR   EMBL; Z98866; CAB11551.1; -; Genomic_DNA.
DR   PIR; T27041; T27041.
DR   RefSeq; NP_499620.1; NM_067219.1.
DR   AlphaFoldDB; Q9XTU6; -.
DR   SMR; Q9XTU6; -.
DR   BioGRID; 41847; 34.
DR   DIP; DIP-24866N; -.
DR   IntAct; Q9XTU6; 4.
DR   STRING; 6239.Y49E10.15; -.
DR   EPD; Q9XTU6; -.
DR   PaxDb; Q9XTU6; -.
DR   PeptideAtlas; Q9XTU6; -.
DR   EnsemblMetazoa; Y49E10.15.1; Y49E10.15.1; WBGene00004919.
DR   GeneID; 176668; -.
DR   KEGG; cel:CELE_Y49E10.15; -.
DR   UCSC; Y49E10.15; c. elegans.
DR   CTD; 176668; -.
DR   WormBase; Y49E10.15; CE22230; WBGene00004919; snr-6.
DR   eggNOG; KOG1774; Eukaryota.
DR   GeneTree; ENSGT00390000012818; -.
DR   HOGENOM; CLU_125186_1_0_1; -.
DR   InParanoid; Q9XTU6; -.
DR   OMA; TIWLYEQ; -.
DR   OrthoDB; 1594132at2759; -.
DR   PhylomeDB; Q9XTU6; -.
DR   Reactome; R-CEL-111367; SLBP independent Processing of Histone Pre-mRNAs.
DR   Reactome; R-CEL-191859; snRNP Assembly.
DR   Reactome; R-CEL-72163; mRNA Splicing - Major Pathway.
DR   Reactome; R-CEL-72165; mRNA Splicing - Minor Pathway.
DR   Reactome; R-CEL-73856; RNA Polymerase II Transcription Termination.
DR   Reactome; R-CEL-77588; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs.
DR   PRO; PR:Q9XTU6; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004919; Expressed in embryo and 4 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0043186; C:P granule; IDA:WormBase.
DR   GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR   GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0005687; C:U4 snRNP; IBA:GO_Central.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IBA:GO_Central.
DR   CDD; cd01718; Sm_E; 1.
DR   InterPro; IPR001163; LSM_dom_euk/arc.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR027078; snRNP-E.
DR   PANTHER; PTHR11193; PTHR11193; 1.
DR   Pfam; PF01423; LSM; 1.
DR   SMART; SM00651; Sm; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Spliceosome.
FT   CHAIN           1..90
FT                   /note="Probable small nuclear ribonucleoprotein E"
FT                   /id="PRO_0000125533"
SQ   SEQUENCE   90 AA;  10610 MW;  B42B8494A6A5A4A2 CRC64;
     MSTRKLNKVM VQPVNLIFRY LQNRTRVQIW LYEDVTHRLE GYIIGFDEFM NVVFDEAEEV
     NMKTKGRNKI GRILLKGDNI TLIHAAQQEA