RUXGL_HUMAN
ID RUXGL_HUMAN Reviewed; 76 AA.
AC A8MWD9;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 2.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Putative small nuclear ribonucleoprotein G-like protein 15;
GN Name=SNRPGP15;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Frontal cortex;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Associated with snRNP U1, U2, U4/U6 and U5. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the snRNP Sm proteins family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC012318; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CK005235; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; A8MWD9; -.
DR SMR; A8MWD9; -.
DR IntAct; A8MWD9; 93.
DR MINT; A8MWD9; -.
DR iPTMnet; A8MWD9; -.
DR MetOSite; A8MWD9; -.
DR PhosphoSitePlus; A8MWD9; -.
DR BioMuta; HGNC:49371; -.
DR EPD; A8MWD9; -.
DR jPOST; A8MWD9; -.
DR MassIVE; A8MWD9; -.
DR MaxQB; A8MWD9; -.
DR PeptideAtlas; A8MWD9; -.
DR PRIDE; A8MWD9; -.
DR GeneCards; SNRPGP15; -.
DR HGNC; HGNC:49371; SNRPGP15.
DR neXtProt; NX_A8MWD9; -.
DR PhylomeDB; A8MWD9; -.
DR PathwayCommons; A8MWD9; -.
DR SignaLink; A8MWD9; -.
DR Pharos; A8MWD9; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; A8MWD9; protein.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0043186; C:P granule; IBA:GO_Central.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0034719; C:SMN-Sm protein complex; IBA:GO_Central.
DR GO; GO:0097526; C:spliceosomal tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0071004; C:U2-type prespliceosome; IBA:GO_Central.
DR GO; GO:0005687; C:U4 snRNP; IBA:GO_Central.
DR GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:InterPro.
DR CDD; cd01719; Sm_G; 1.
DR InterPro; IPR044641; Lsm7/SmG-like.
DR InterPro; IPR001163; LSM_dom_euk/arc.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR034098; Sm_G.
DR PANTHER; PTHR10553; PTHR10553; 1.
DR Pfam; PF01423; LSM; 1.
DR SMART; SM00651; Sm; 1.
DR SUPFAM; SSF50182; SSF50182; 1.
PE 5: Uncertain;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Ribonucleoprotein; RNA-binding; Spliceosome.
FT CHAIN 1..76
FT /note="Putative small nuclear ribonucleoprotein G-like
FT protein 15"
FT /id="PRO_0000348240"
FT CONFLICT 50
FT /note="T -> I (in Ref. 2; CK005235)"
FT /evidence="ECO:0000305"
FT CONFLICT 68
FT /note="I -> F (in Ref. 2; CK005235)"
FT /evidence="ECO:0000305"
FT CONFLICT 73
FT /note="L -> K (in Ref. 2; CK005235)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 76 AA; 8544 MW; BF93159251E1E44A CRC64;
MSKAHPPELK KFTDKKFSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT SGQQKNIGMV
EIRGNSIIML EALERV