RUXG_CAEEL
ID RUXG_CAEEL Reviewed; 77 AA.
AC Q9N4G9;
DT 28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable small nuclear ribonucleoprotein G;
DE Short=snRNP-G;
DE AltName: Full=Sm protein G;
DE Short=Sm-G;
DE Short=SmG;
GN Name=snr-7; ORFNames=Y71F9B.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Bristol N2;
RA Kohara Y., Shin-i T., Suzuki Y., Sugano S., Potdevin M., Thierry-Mieg Y.,
RA Thierry-Mieg D., Thierry-Mieg J.;
RT "The Caenorhabditis elegans transcriptome project, a complementary view of
RT the genome.";
RL Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in pre-mRNA splicing as a core component of the
CC spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins
CC (snRNPs), the building blocks of the spliceosome (By similarity).
CC {ECO:0000250|UniProtKB:P62308}.
CC -!- SUBUNIT: Core component of the spliceosomal U1, U2, U4 and U5 small
CC nuclear ribonucleoproteins (snRNPs), the building blocks of the
CC spliceosome. {ECO:0000250|UniProtKB:P62308}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P62308}. Nucleus {ECO:0000250|UniProtKB:P62308}.
CC -!- SIMILARITY: Belongs to the snRNP Sm proteins family. {ECO:0000305}.
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DR EMBL; FO081276; CCD70411.1; -; Genomic_DNA.
DR EMBL; AF303264; AAG50222.1; -; mRNA.
DR RefSeq; NP_491032.1; NM_058631.5.
DR AlphaFoldDB; Q9N4G9; -.
DR SMR; Q9N4G9; -.
DR BioGRID; 37315; 34.
DR IntAct; Q9N4G9; 5.
DR STRING; 6239.Y71F9B.4.1; -.
DR EPD; Q9N4G9; -.
DR PaxDb; Q9N4G9; -.
DR PeptideAtlas; Q9N4G9; -.
DR EnsemblMetazoa; Y71F9B.4.1; Y71F9B.4.1; WBGene00004920.
DR GeneID; 171834; -.
DR KEGG; cel:CELE_Y71F9B.4; -.
DR UCSC; Y71F9B.4; c. elegans.
DR CTD; 171834; -.
DR WormBase; Y71F9B.4; CE22871; WBGene00004920; snr-7.
DR eggNOG; KOG1780; Eukaryota.
DR GeneTree; ENSGT00940000176059; -.
DR HOGENOM; CLU_076902_10_1_1; -.
DR InParanoid; Q9N4G9; -.
DR OMA; WGFDPFI; -.
DR OrthoDB; 1593201at2759; -.
DR PhylomeDB; Q9N4G9; -.
DR Reactome; R-CEL-111367; SLBP independent Processing of Histone Pre-mRNAs.
DR Reactome; R-CEL-191859; snRNP Assembly.
DR Reactome; R-CEL-72163; mRNA Splicing - Major Pathway.
DR Reactome; R-CEL-72165; mRNA Splicing - Minor Pathway.
DR Reactome; R-CEL-73856; RNA Polymerase II Transcription Termination.
DR Reactome; R-CEL-77588; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs.
DR PRO; PR:Q9N4G9; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00004920; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0043186; C:P granule; IDA:WormBase.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0034719; C:SMN-Sm protein complex; IBA:GO_Central.
DR GO; GO:0097526; C:spliceosomal tri-snRNP complex; IBA:GO_Central.
DR GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0071004; C:U2-type prespliceosome; IBA:GO_Central.
DR GO; GO:0005687; C:U4 snRNP; IBA:GO_Central.
DR GO; GO:0005682; C:U5 snRNP; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:InterPro.
DR CDD; cd01719; Sm_G; 1.
DR InterPro; IPR044641; Lsm7/SmG-like.
DR InterPro; IPR001163; LSM_dom_euk/arc.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR034098; Sm_G.
DR PANTHER; PTHR10553; PTHR10553; 1.
DR Pfam; PF01423; LSM; 1.
DR SMART; SM00651; Sm; 1.
DR SUPFAM; SSF50182; SSF50182; 1.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Ribonucleoprotein; RNA-binding; Spliceosome.
FT CHAIN 1..77
FT /note="Probable small nuclear ribonucleoprotein G"
FT /id="PRO_0000125547"
SQ SEQUENCE 77 AA; 8743 MW; DD0AC56F20850A0E CRC64;
MSKTHPPELK KYMDKEMDLK LNGNRRVSGI LRGFDPFMNM VIDEAVEYQK DGGSVNLGMT
VIRGNSVVIM EPKERIS
