ID   RV162_CANAL             Reviewed;         335 AA.
AC   Q59PE4; A0A1D8PFG9;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=RVS161-like protein RVS162 {ECO:0000305};
GN   Name=RVS162 {ECO:0000303|PubMed:19596778};
GN   OrderedLocusNames=CAALFM_C112730WA; ORFNames=CaO19.6349;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN   [4]
RP   IDENTIFICATION, AND DISRUPTION PHENOTYPE.
RX   PubMed=19596778; DOI=10.1128/iai.00683-09;
RA   Douglas L.M., Martin S.W., Konopka J.B.;
RT   "BAR domain proteins Rvs161 and Rvs167 contribute to Candida albicans
RT   endocytosis, morphogenesis, and virulence.";
RL   Infect. Immun. 77:4150-4160(2009).
CC   -!- FUNCTION: Component of a cytoskeletal structure that is required for
CC       membrane curvature. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:P25343}.
CC   -!- DISRUPTION PHENOTYPE: Does not display the endocytic, hyphal growth,
CC       virulence, or cell wall defects exhibited by disruption in related
CC       RVS161 or RVS167. {ECO:0000269|PubMed:19596778}.
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DR   EMBL; CP017623; AOW26888.1; -; Genomic_DNA.
DR   RefSeq; XP_711567.2; XM_706475.2.
DR   AlphaFoldDB; Q59PE4; -.
DR   SMR; Q59PE4; -.
DR   STRING; 237561.Q59PE4; -.
DR   PRIDE; Q59PE4; -.
DR   GeneID; 3646820; -.
DR   KEGG; cal:CAALFM_C112730WA; -.
DR   CGD; CAL0000191779; RVS162.
DR   VEuPathDB; FungiDB:C1_12730W_A; -.
DR   eggNOG; KOG3771; Eukaryota.
DR   HOGENOM; CLU_072096_0_0_1; -.
DR   InParanoid; Q59PE4; -.
DR   OrthoDB; 1172471at2759; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0030479; C:actin cortical patch; IBA:GO_Central.
DR   GO; GO:0043332; C:mating projection tip; IBA:GO_Central.
DR   GO; GO:0031097; C:medial cortex; IBA:GO_Central.
DR   GO; GO:1990528; C:Rvs161p-Rvs167p complex; IBA:GO_Central.
DR   GO; GO:0051666; P:actin cortical patch localization; IBA:GO_Central.
DR   GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR   GO; GO:0097320; P:plasma membrane tubulation; IBA:GO_Central.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   Pfam; PF03114; BAR; 1.
DR   SMART; SM00721; BAR; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   PROSITE; PS51021; BAR; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..335
FT                   /note="RVS161-like protein RVS162"
FT                   /id="PRO_0000430557"
FT   DOMAIN          17..310
FT                   /note="BAR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00361"
FT   REGION          105..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          30..56
FT                   /evidence="ECO:0000255"
FT   COILED          222..259
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   335 AA;  39383 MW;  A44FCFBA8110F0BD CRC64;
     MSWIGIKKAI NRAGTQVMLK TGHIEQTIDK EYEFQEKRYR TMEENSIKLQ KNLRLYLDSL
     RLLTNSQINI AESLNSFYGT NNDKRSSNIS RTGSVNTGDK IQTIHEEEGE EKEEEENDNT
     TTTTTTTTTT ITTTNTTYNY NNLIQEYYAT IKQLNDSCIA NLENPYNQTV LNPIARFNSY
     YIEINEIIKK RHNKLLDYDA MKNKLRKLIE NPTTNISPSM KTNIIELNHN QYEEKLKIYN
     QELTEVESKY VEINNQLLIE LPKLINHRIS YFDPSFESFV KIQLRFFNEN YHVLNQLQLK
     LDAQTRQDYI EGKLEDRIDD VLRKMKKLDI TSGLD