RVE1_ARATH
ID RVE1_ARATH Reviewed; 387 AA.
AC F4KGY6; Q93WC6; Q9FFI1;
DT 22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Protein REVEILLE 1;
GN Name=RVE1; OrderedLocusNames=At5g17300; ORFNames=MKP11.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 107-387.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, INDUCTION, DISRUPTION PHENOTYPE, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19805390; DOI=10.1073/pnas.0813035106;
RA Rawat R., Schwartz J., Jones M.A., Sairanen I., Cheng Y., Andersson C.R.,
RA Zhao Y., Ljung K., Harmer S.L.;
RT "REVEILLE1, a Myb-like transcription factor, integrates the circadian clock
RT and auxin pathways.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:16883-16888(2009).
RN [5]
RP FUNCTION, INDUCTION BY COLD, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=23240770; DOI=10.1111/pce.12054;
RA Meissner M., Orsini E., Ruschhaupt M., Melchinger A.E., Hincha D.K.,
RA Heyer A.G.;
RT "Mapping quantitative trait loci for freezing tolerance in a recombinant
RT inbred line population of Arabidopsis thaliana accessions Tenela and C24
RT reveals REVEILLE1 as negative regulator of cold acclimation.";
RL Plant Cell Environ. 36:1256-1267(2013).
CC -!- FUNCTION: Morning-phased transcription factor integrating the circadian
CC clock and auxin pathways. Binds to the evening element (EE) of
CC promoters. Does not act within the central clock, but regulates free
CC auxin levels in a time-of-day specific manner. Positively regulates the
CC expression of YUC8 during the day, but has no effect during the night.
CC Negative regulator of freezing tolerance. {ECO:0000269|PubMed:19805390,
CC ECO:0000269|PubMed:23240770}.
CC -!- INTERACTION:
CC F4KGY6; Q9XGN1: TTG1; NbExp=4; IntAct=EBI-15194459, EBI-395803;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- INDUCTION: Circadian-regulation. Peak of transcript abundance near
CC subjective dawn. Down-regulated and strongly decreased amplitude of
CC circadian oscillation upon cold treatment.
CC {ECO:0000269|PubMed:19805390, ECO:0000269|PubMed:23240770}.
CC -!- DISRUPTION PHENOTYPE: No effect on the regulation of core clock
CC associated genes, but shorter hypocotyl length and higher freezing
CC tolerance. Rve1 and rve2 double mutant has no alteration in the period
CC or phase of the clock. Rve1, rve2 and rve7 triple mutant has no
CC alteration in the period or phase of the clock.
CC {ECO:0000269|PubMed:19805390, ECO:0000269|PubMed:23240770}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK55663.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB10517.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB005238; BAB10517.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED92410.1; -; Genomic_DNA.
DR EMBL; AF378860; AAK55663.1; ALT_INIT; mRNA.
DR EMBL; AY050467; AAK91480.1; -; mRNA.
DR RefSeq; NP_568344.2; NM_121736.3.
DR AlphaFoldDB; F4KGY6; -.
DR SMR; F4KGY6; -.
DR BioGRID; 16871; 51.
DR IntAct; F4KGY6; 44.
DR STRING; 3702.AT5G17300.1; -.
DR PaxDb; F4KGY6; -.
DR PRIDE; F4KGY6; -.
DR ProteomicsDB; 228042; -.
DR EnsemblPlants; AT5G17300.1; AT5G17300.1; AT5G17300.
DR GeneID; 831595; -.
DR Gramene; AT5G17300.1; AT5G17300.1; AT5G17300.
DR KEGG; ath:AT5G17300; -.
DR Araport; AT5G17300; -.
DR TAIR; locus:2167210; AT5G17300.
DR eggNOG; KOG0724; Eukaryota.
DR HOGENOM; CLU_030536_0_0_1; -.
DR InParanoid; F4KGY6; -.
DR OrthoDB; 1118093at2759; -.
DR PRO; PR:F4KGY6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KGY6; baseline and differential.
DR Genevisible; F4KGY6; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IMP:TAIR.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IMP:TAIR.
DR GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR GO; GO:0010600; P:regulation of auxin biosynthetic process; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd00167; SANT; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 1: Evidence at protein level;
KW Biological rhythms; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..387
FT /note="Protein REVEILLE 1"
FT /id="PRO_0000424835"
FT DOMAIN 50..104
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 77..100
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 42981 MW; FFA9AF9E52ECB33F CRC64;
MASSPLTANV QGTNASLRNR DEETADKQIQ FNDQSFGGND YAPKVRKPYT ITKERERWTD
EEHKKFVEAL KLYGRAWRRI EEHVGSKTAV QIRSHAQKFF SKVAREATGG DGSSVEPIVI
PPPRPKRKPA HPYPRKFGNE ADQTSRSVSP SERDTQSPTS VLSTVGSEAL CSLDSSSPNR
SLSPVSSASP PAALTTTANA PEELETLKLE LFPSERLLNR ESSIKEPTKQ SLKLFGKTVL
VSDSGMSSSL TTSTYCKSPI QPLPRKLSSS KTLPIIRNSQ EELLSCWIQV PLKQEDVENR
CLDSGKAVQN EGSSTGSNTG SVDDTGHTEK TTEPETMLCQ WEFKPSERSA FSELRRTNSE
SNSRGFGPYK KRKMVTEEEE HEIHLHL
