ID   RWD2A_MOUSE             Reviewed;         292 AA.
AC   Q9D9S3;
DT   15-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=RWD domain-containing protein 2A;
GN   Name=Rwdd2a; Synonyms=Rwdd2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000312|EMBL:BAB24638.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
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DR   EMBL; AK006533; BAB24638.1; -; mRNA.
DR   CCDS; CCDS23382.1; -.
DR   RefSeq; NP_001139441.1; NM_001145969.1.
DR   AlphaFoldDB; Q9D9S3; -.
DR   SMR; Q9D9S3; -.
DR   STRING; 10090.ENSMUSP00000034988; -.
DR   iPTMnet; Q9D9S3; -.
DR   PhosphoSitePlus; Q9D9S3; -.
DR   MaxQB; Q9D9S3; -.
DR   PaxDb; Q9D9S3; -.
DR   PRIDE; Q9D9S3; -.
DR   ProteomicsDB; 260959; -.
DR   GeneID; 69519; -.
DR   KEGG; mmu:69519; -.
DR   CTD; 112611; -.
DR   MGI; MGI:1916769; Rwdd2a.
DR   eggNOG; ENOG502QTUP; Eukaryota.
DR   InParanoid; Q9D9S3; -.
DR   PhylomeDB; Q9D9S3; -.
DR   BioGRID-ORCS; 69519; 1 hit in 72 CRISPR screens.
DR   PRO; PR:Q9D9S3; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q9D9S3; protein.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR010541; Prp3_C.
DR   InterPro; IPR006575; RWD-domain.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR017359; UCP038021_RWD.
DR   PANTHER; PTHR15955; PTHR15955; 1.
DR   Pfam; PF06544; DUF1115; 1.
DR   Pfam; PF05773; RWD; 1.
DR   PIRSF; PIRSF038021; UCP038021_RWDD2; 1.
DR   SMART; SM00591; RWD; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50908; RWD; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..292
FT                   /note="RWD domain-containing protein 2A"
FT                   /id="PRO_0000097544"
FT   DOMAIN          14..134
FT                   /note="RWD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00179,
FT                   ECO:0000305"
SQ   SEQUENCE   292 AA;  33916 MW;  6ED82248DEA9E186 CRC64;
     MSGSVKESLQ LQLLEMEMLF SMFPNQGEVK LEDVNALTNI KRYLEGTREA LPPNIEFVIT
     LQIEEPKVTI DLQVTMPHNY PYVALQLFGR SPELDRQQQL LLNQALSAYL RTFDPGELCV
     CAAIQWLQDN SASYFLTRKL SDEPSVQAKP VKNTFLRMWI YSHHIYQQDL RKKILEVGKR
     LDVTGFCMTG KPGIICVEGF KNHCEEFWHT IRYPNWKHIS CKHAESVETE GDGEDLRLFH
     SFEELLLEAH GDYGLRNDYH MNLGQFLEFL RKHKSEHVFQ ILFGIESKSS ES