RWDD4_MOUSE
ID RWDD4_MOUSE Reviewed; 188 AA.
AC Q9CPR1;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=RWD domain-containing protein 4;
GN Name=Rwdd4; Synonyms=Rwdd4a;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Lung, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Eye;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK004597; BAB23398.1; -; mRNA.
DR EMBL; AK005797; BAB24243.1; -; mRNA.
DR EMBL; BC016198; AAH16198.1; -; mRNA.
DR CCDS; CCDS22297.1; -.
DR RefSeq; NP_987103.1; NM_203507.3.
DR AlphaFoldDB; Q9CPR1; -.
DR SMR; Q9CPR1; -.
DR IntAct; Q9CPR1; 1.
DR MINT; Q9CPR1; -.
DR STRING; 10090.ENSMUSP00000033973; -.
DR iPTMnet; Q9CPR1; -.
DR PhosphoSitePlus; Q9CPR1; -.
DR EPD; Q9CPR1; -.
DR MaxQB; Q9CPR1; -.
DR PaxDb; Q9CPR1; -.
DR PeptideAtlas; Q9CPR1; -.
DR PRIDE; Q9CPR1; -.
DR ProteomicsDB; 256551; -.
DR Antibodypedia; 45760; 44 antibodies from 10 providers.
DR Ensembl; ENSMUST00000033973; ENSMUSP00000033973; ENSMUSG00000031568.
DR GeneID; 192174; -.
DR KEGG; mmu:192174; -.
DR UCSC; uc033jfm.1; mouse.
DR CTD; 192174; -.
DR MGI; MGI:2681000; Rwdd4a.
DR VEuPathDB; HostDB:ENSMUSG00000031568; -.
DR eggNOG; KOG4018; Eukaryota.
DR GeneTree; ENSGT00390000015545; -.
DR HOGENOM; CLU_123949_0_0_1; -.
DR InParanoid; Q9CPR1; -.
DR OMA; LGCGMTY; -.
DR OrthoDB; 1549838at2759; -.
DR PhylomeDB; Q9CPR1; -.
DR TreeFam; TF326409; -.
DR BioGRID-ORCS; 192174; 5 hits in 71 CRISPR screens.
DR ChiTaRS; Rwdd4a; mouse.
DR PRO; PR:Q9CPR1; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q9CPR1; protein.
DR Bgee; ENSMUSG00000031568; Expressed in condyle and 253 other tissues.
DR ExpressionAtlas; Q9CPR1; baseline and differential.
DR Genevisible; Q9CPR1; MM.
DR Gene3D; 3.10.110.10; -; 1.
DR InterPro; IPR006575; RWD-domain.
DR InterPro; IPR042770; RWDD4.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR21275; PTHR21275; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00591; RWD; 1.
DR SUPFAM; SSF54495; SSF54495; 1.
DR PROSITE; PS50908; RWD; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..188
FT /note="RWD domain-containing protein 4"
FT /id="PRO_0000076308"
FT DOMAIN 9..111
FT /note="RWD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00179"
FT REGION 132..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21138 MW; 45C4D6B56E78BE6E CRC64;
MGANEDQEME LEALRSIYEG DNSFRELSPV SFQYRIGEDG DPKAFLIEVS WTETYPQTAP
VISMNAFFNN TISSAVKQSI LAKLQEAVEV NLGTAMTYTL FEYAKDHKEQ FMENHHPGNS
ATPVANIISV ETPTTAPSSK KKEKKEQLSK AQKRKLADKT DHKGELPRGW NWVDVVKHLS
KTGSKDDE
