RX24L_ARATH
ID RX24L_ARATH Reviewed; 899 AA.
AC Q9C646; Q9SM04;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable disease resistance protein RXW24L;
GN Name=RXW24L; OrderedLocusNames=At1g58410; ORFNames=F9K23.6, X7J.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NUCLEOTIDE SEQUENCE [MRNA] OF
RP 584-899.
RC STRAIN=cv. Columbia;
RX PubMed=10548732; DOI=10.1016/s0378-1119(99)00403-5;
RA Kato A., Suzuki M., Kuwahara A., Ooe H., Higano-Inaba K., Komeda Y.;
RT "Isolation and analysis of cDNA within a 300 kb Arabidopsis thaliana
RT genomic region located around the 100 map unit of chromosome 1.";
RL Gene 239:309-316(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Potential disease resistance protein.
CC -!- DOMAIN: The LRR repeats probably act as specificity determinant of
CC pathogen recognition. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC of disease resistance gene homologs;
CC URL="http://niblrrs.ucdavis.edu";
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DR EMBL; AB008019; BAA88266.1; -; mRNA.
DR EMBL; AB077822; BAB83873.1; -; Genomic_DNA.
DR EMBL; AC082643; AAG50648.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33546.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61068.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM61069.1; -; Genomic_DNA.
DR PIR; H96617; H96617.
DR PIR; T52464; T52464.
DR RefSeq; NP_001319267.1; NM_001333834.1.
DR RefSeq; NP_001323309.1; NM_001333835.1.
DR RefSeq; NP_176137.1; NM_104621.1.
DR AlphaFoldDB; Q9C646; -.
DR SMR; Q9C646; -.
DR STRING; 3702.AT1G58410.1; -.
DR PaxDb; Q9C646; -.
DR PRIDE; Q9C646; -.
DR EnsemblPlants; AT1G58410.1; AT1G58410.1; AT1G58410.
DR EnsemblPlants; AT1G58410.2; AT1G58410.2; AT1G58410.
DR EnsemblPlants; AT1G58410.4; AT1G58410.4; AT1G58410.
DR GeneID; 842210; -.
DR Gramene; AT1G58410.1; AT1G58410.1; AT1G58410.
DR Gramene; AT1G58410.2; AT1G58410.2; AT1G58410.
DR Gramene; AT1G58410.4; AT1G58410.4; AT1G58410.
DR KEGG; ath:AT1G58410; -.
DR Araport; AT1G58410; -.
DR TAIR; locus:2037623; AT1G58410.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_25_4_1; -.
DR InParanoid; Q9C646; -.
DR OMA; WELFENI; -.
DR OrthoDB; 164862at2759; -.
DR PhylomeDB; Q9C646; -.
DR PRO; PR:Q9C646; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C646; baseline and differential.
DR Genevisible; Q9C646; AT.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.8.430; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; PTHR23155; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Nucleotide-binding; Plant defense;
KW Reference proteome; Repeat.
FT CHAIN 1..899
FT /note="Probable disease resistance protein RXW24L"
FT /id="PRO_0000212776"
FT DOMAIN 143..455
FT /note="NB-ARC"
FT COILED 13..50
FT /evidence="ECO:0000255"
FT BINDING 189..196
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 899 AA; 104333 MW; 99DC7FF6D1A5335F CRC64;
MELVSFGVEK LWDRLSQEYD QFKGVEDQVT ELKSNLNLLK SFLKDADAKK HISEMVRHCV
EEIKDIVYDT EDIIETFILK EKVEMKRGIM KRIKRFASTI MDRRELASDI GGISKRISKV
IQDMQSFGVQ QIITDGSRSS HPLQERQREM RHTFSRDSEN DFVGMEANVK KLVGYLVEKD
DYQIVSLTGM GGLGKTTLAR QVFNHDVVKD RFDGFAWVSV SQEFTRISVW QTILQNLTSK
ERKDEIQNMK EADLHDDLFR LLESSKTLIV LDDIWKEEDW DLIKPIFPPK KGWKVLLTSR
TESIAMRGDT TYISFKPKCL SIPDSWTLFQ SIAMPRKDTS EFKVDEEMEN MGKKMIKHCG
GLSLAVKVLG GLLAAKYTLH DWKRLSENIG SHIVERTSGN NSSIDHVLSV SFEELPNYLK
HCFLYLAHFP EDHEIDVEKL HYYWAAEGIS ERRRYDGETI RDTGDSYIEE LVRRNMVISE
RDVMTSRFET CRLHDMMREI CLFKAKEENF LQIVSNHSPT SNPQTLGASR RFVLHNPTTL
HVERYKNNPK LRSLVVVYDD IGNRRWMLSG SIFTRVKLLR VLDLVQAKFK GGKLPSDIGK
LIHLRYLSLK DAKVSHLPSS LRNLVLLIYL DIRTDFTDIF VPNVFMGMRE LRYLELPRFM
HEKTKLELSN LEKLEALENF STKSSSLEDL RGMVRLRTLV IILSEGTSLQ TLSASVCGLR
HLENFKIMEN AGVNRMGEER MVLDFTYLKK LTLSIEMPRL PKIQHLPSHL TVLDLSYCCL
EEDPMPILEK LLELKDLSLD YLSFSGRKMV CSAGGFPQLR KLALDEQEEW EEWIVEEGSM
SRLHTLSIWS STLKELPDGL RFIYSLKNLI MGKSWMERLS ERGEEFYKVQ NIPFIKFSS
