ID   S10AA_MACMU             Reviewed;          97 AA.
AC   P62504; Q6PHU3; Q6Y5H4;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Protein S100-A10;
DE   AltName: Full=Calpactin I light chain;
DE   AltName: Full=Calpactin-1 light chain;
DE   AltName: Full=S100 calcium-binding protein A10;
GN   Name=S100A10; Synonyms=CAL1L;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Sun X.-Y., Tan Y.-F., Qin L., Bai S.-X., Li F.-X., Qiu W., Piao Y.-S.,
RA   Wang Y.-L.;
RT   "Molecular cloning of genes critical to embryo implantation from Rhesus
RT   monkey by suppression subtractive hybridization.";
RL   Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Because S100A10 induces the dimerization of ANXA2/p36, it may
CC       function as a regulator of protein phosphorylation in that the ANXA2
CC       monomer is the preferred target (in vitro) of tyrosine-specific kinase.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterotetramer containing 2 light chains of S100A10/p11 and 2
CC       heavy chains of ANXA2/p36 (By similarity). Interacts with SCN10A (By
CC       similarity). Interacts with TASOR (By similarity).
CC       {ECO:0000250|UniProtKB:P05943, ECO:0000250|UniProtKB:P08207,
CC       ECO:0000250|UniProtKB:P60903}.
CC   -!- MISCELLANEOUS: Does not appear to bind calcium. Contains 2 ancestral
CC       calcium site related to EF-hand domains that have lost their ability to
CC       bind calcium.
CC   -!- SIMILARITY: Belongs to the S-100 family. {ECO:0000305}.
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DR   EMBL; AY179865; AAO21200.1; -; mRNA.
DR   RefSeq; NP_001028124.1; NM_001032952.3.
DR   RefSeq; NP_001265347.1; NM_001278418.1.
DR   RefSeq; XP_015005957.1; XM_015150471.1.
DR   RefSeq; XP_015005963.1; XM_015150477.1.
DR   RefSeq; XP_015005974.1; XM_015150488.1.
DR   AlphaFoldDB; P62504; -.
DR   SMR; P62504; -.
DR   STRING; 9544.ENSMMUP00000039024; -.
DR   Ensembl; ENSMMUT00000090627; ENSMMUP00000072967; ENSMMUG00000052533.
DR   GeneID; 574374; -.
DR   KEGG; mcc:574374; -.
DR   CTD; 6281; -.
DR   VEuPathDB; HostDB:ENSMMUG00000052533; -.
DR   VGNC; VGNC:106491; S100A10.
DR   eggNOG; ENOG502S6TB; Eukaryota.
DR   GeneTree; ENSGT00940000154197; -.
DR   HOGENOM; CLU_138624_2_1_1; -.
DR   InParanoid; P62504; -.
DR   OMA; SEMEHAP; -.
DR   TreeFam; TF332727; -.
DR   Proteomes; UP000006718; Chromosome 1.
DR   Bgee; ENSMMUG00000052533; Expressed in lung and 23 other tissues.
DR   ExpressionAtlas; P62504; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IBA:GO_Central.
DR   GO; GO:0044325; F:transmembrane transporter binding; IBA:GO_Central.
DR   CDD; cd05024; S-100A10; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR028476; S100-A10.
DR   InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR   InterPro; IPR013787; S100_Ca-bd_sub.
DR   PANTHER; PTHR11639:SF74; PTHR11639:SF74; 1.
DR   Pfam; PF01023; S_100; 1.
DR   SMART; SM01394; S_100; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00303; S100_CABP; 1.
PE   3: Inferred from homology;
KW   Acetylation; Isopeptide bond; Reference proteome; Ubl conjugation.
FT   CHAIN           1..97
FT                   /note="Protein S100-A10"
FT                   /id="PRO_0000144003"
FT   REGION          60..71
FT                   /note="Ancestral calcium site"
FT   MOD_RES         23
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
FT   MOD_RES         28
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
FT   MOD_RES         37
FT                   /note="N6-acetyllysine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
FT   MOD_RES         54
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
FT   MOD_RES         57
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
FT   CROSSLNK        37
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2); alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P60903"
SQ   SEQUENCE   97 AA;  11203 MW;  3E8E03A6E7DD7A8D CRC64;
     MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD
     QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK