ID   S115A_GORGO             Reviewed;         108 AA.
AC   A7K6Y8;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Protein S100-A15A;
DE   AltName: Full=S100 calcium-binding protein A15A;
GN   Name=S100A15A;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=17642472; DOI=10.1093/molbev/msm146;
RA   Hahn Y., Jeong S., Lee B.;
RT   "Inactivation of MOXD2 and S100A15A by exon deletion during human
RT   evolution.";
RL   Mol. Biol. Evol. 24:2203-2212(2007).
CC   -!- SIMILARITY: Belongs to the S-100 family. {ECO:0000305}.
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DR   EMBL; EF044237; ABO30561.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7K6Y8; -.
DR   SMR; A7K6Y8; -.
DR   STRING; 9593.ENSGGOP00000024236; -.
DR   eggNOG; ENOG502SXYF; Eukaryota.
DR   HOGENOM; CLU_138624_5_0_1; -.
DR   InParanoid; A7K6Y8; -.
DR   OMA; FQIIHCF; -.
DR   Proteomes; UP000001519; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IBA:GO_Central.
DR   GO; GO:0042056; F:chemoattractant activity; IBA:GO_Central.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   CDD; cd00213; S-100; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR034325; S-100_dom.
DR   InterPro; IPR013787; S100_Ca-bd_sub.
DR   InterPro; IPR028495; S100A15A.
DR   PANTHER; PTHR11639:SF29; PTHR11639:SF29; 1.
DR   Pfam; PF01023; S_100; 1.
DR   SMART; SM00054; EFh; 1.
DR   SMART; SM01394; S_100; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Calcium; Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..108
FT                   /note="Protein S100-A15A"
FT                   /id="PRO_0000320088"
FT   DOMAIN          53..88
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         66
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_note="high affinity"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         68
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_note="high affinity"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         70
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_note="high affinity"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         72
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_note="high affinity"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         77
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /ligand_note="high affinity"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ   SEQUENCE   108 AA;  12908 MW;  47336632AF05C94E CRC64;
     MTDTPVEESL FQIIHCFHQY AARQGDMETL SLQELQALLM DNMPRFMDSL GQKEPYYVTE
     LFQATDKNRD NQICFDEFLY ILGKLVKDYH LQYHRQLCAR YCAQHSLY