ID   S11IP_XENTR             Reviewed;        1129 AA.
AC   Q6P4K6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Serine/threonine-protein kinase 11-interacting protein;
GN   Name=stk11ip;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the STK11IP family. {ECO:0000305}.
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DR   EMBL; BC063361; AAH63361.1; -; mRNA.
DR   RefSeq; NP_989177.1; NM_203846.1.
DR   AlphaFoldDB; Q6P4K6; -.
DR   SMR; Q6P4K6; -.
DR   STRING; 8364.ENSXETP00000059904; -.
DR   PaxDb; Q6P4K6; -.
DR   PRIDE; Q6P4K6; -.
DR   GeneID; 394784; -.
DR   KEGG; xtr:394784; -.
DR   CTD; 114790; -.
DR   Xenbase; XB-GENE-947946; stk11ip.
DR   eggNOG; KOG1859; Eukaryota.
DR   InParanoid; Q6P4K6; -.
DR   OrthoDB; 1041637at2759; -.
DR   Reactome; R-XTR-6798695; Neutrophil degranulation.
DR   Proteomes; UP000008143; Chromosome 9.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR   GO; GO:0008104; P:protein localization; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR031782; LIP1_N.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF15904; LIP1; 1.
DR   SMART; SM00369; LRR_TYP; 3.
DR   PROSITE; PS51450; LRR; 6.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..1129
FT                   /note="Serine/threonine-protein kinase 11-interacting
FT                   protein"
FT                   /id="PRO_0000317466"
FT   REPEAT          107..128
FT                   /note="LRR 1"
FT   REPEAT          130..150
FT                   /note="LRR 2"
FT   REPEAT          162..183
FT                   /note="LRR 3"
FT   REPEAT          185..206
FT                   /note="LRR 4"
FT   REPEAT          208..229
FT                   /note="LRR 5"
FT   REPEAT          232..253
FT                   /note="LRR 6"
FT   REPEAT          254..275
FT                   /note="LRR 7"
FT   REPEAT          279..300
FT                   /note="LRR 8"
FT   REGION          335..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..678
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          696..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          730..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..355
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..392
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        433..469
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1129 AA;  126056 MW;  FFA11F20A0DB9BD7 CRC64;
     MPSEVPESLV QALAQILHEH GDKVLDGSRI LALLTPCLQV VTRLFEQLFP RGPGTGFQAL
     PAHPADSVPI LRAQFMLDML QKTPSLKLVH PAECPRQFDV NIFPFKSLRS LELRCLPPHC
     LRGLRSVYSQ LEVLTCYRCV SSLEEVIALC GGDLSSALPW LVLHTLDFSY NTLKNLDGSL
     ELLNSLKILD LSHNQITECG SYLKVLSELQ YLNLGYNHLT AVPELSVGNT AKLHSLILKH
     NQLSGTSGLE NLPNLQHLDL SYNLLLEHSQ LSGLARLHNL KQLFLEGNPL YFQKDYRALT
     AQHLSHKASD NVLLDGKLLS SSEIMNAQAF GEKVRLQPSS SATESSCTGD LTDSYSAAEK
     SAPRLPRKKS RVKVRTASIS ERSDSEYERR GQPIVLQHQR EIERTDSFRE QYGEDWLQYR
     PHLEGELDPE YVNRPHSPPP RASPSPTAPS SVPKQKSPVP APEPSPSPKS GHVAPDDQLM
     EKAEEGLEEH LWGLQEAKKP NEEEGLIGGA LCSPVVVCPV LNGQPRNPDW PWVFLRITLH
     FLLEMDPERG RILLKRELRS LRGIQTSLAP WKCNGEEQEL PLLTLSFDSV CEEKQTVNYI
     VLDNSPESSV TTLLDLLRPM LERNLREKAE SQDELTRMQC LKCKAEFRNE VDGGDIYSPE
     SLQQGKEPTA GLHRNHTGDA SCPSCGSLHI ILAPLNPTGE TSTPLRPLSA EPPQGDDGGG
     GLAAKSFYLS EDEDSSETDS SPNTAPSEAE STIFYSFDTE GQDQQSAQDT GRSSLTGSYK
     YTALNQSGAL SQDGWQISPG PASTLDFRLV DHRLKLYLDM EVLNGDMEEF RCCMKVPVIR
     FGKVSEFWAV VAVSNQKIYF LEITGEIRDN PSDWLQPIES QSLTSLARLH VGLQEHSLHL
     GFGGSGGAYT LLTRNQQHCR VFHKHMLDVL AELPARYLGN IQQSSEEPIT PQHRLWPFLQ
     DKVGAPESNA PPRFLYVPLF FLREDIVSPN ADSPCANANS QLPLLNTASP AALIQGAAAA
     APLSLLVTRT HMYLLEEDHQ WLPDTLDTEL PDSVQMKEKQ PISNISSVHL FQSATLHLRI
     HLYNETQQNE SAWLLWTEDP DRTREIVEWL REPWEAEYHI HFNPVTHNT