S18L2_MOUSE
ID S18L2_MOUSE Reviewed; 77 AA.
AC Q9D174;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=SS18-like protein 2;
GN Name=Ss18l2; Synonyms=Deb1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the SS18 family. {ECO:0000305}.
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DR EMBL; AK003863; BAB23045.1; -; mRNA.
DR EMBL; BC027548; AAH27548.1; -; mRNA.
DR CCDS; CCDS40811.1; -.
DR RefSeq; NP_081070.1; NM_026794.2.
DR AlphaFoldDB; Q9D174; -.
DR SMR; Q9D174; -.
DR STRING; 10090.ENSMUSP00000035113; -.
DR PhosphoSitePlus; Q9D174; -.
DR EPD; Q9D174; -.
DR jPOST; Q9D174; -.
DR MaxQB; Q9D174; -.
DR PaxDb; Q9D174; -.
DR PRIDE; Q9D174; -.
DR ProteomicsDB; 256814; -.
DR Antibodypedia; 29253; 26 antibodies from 14 providers.
DR Ensembl; ENSMUST00000035113; ENSMUSP00000035113; ENSMUSG00000032526.
DR GeneID; 26901; -.
DR KEGG; mmu:26901; -.
DR UCSC; uc009sdo.1; mouse.
DR CTD; 51188; -.
DR MGI; MGI:1349474; Ss18l2.
DR VEuPathDB; HostDB:ENSMUSG00000032526; -.
DR eggNOG; KOG3227; Eukaryota.
DR GeneTree; ENSGT00940000160407; -.
DR HOGENOM; CLU_164146_1_0_1; -.
DR InParanoid; Q9D174; -.
DR OMA; GRAHECV; -.
DR OrthoDB; 1442230at2759; -.
DR PhylomeDB; Q9D174; -.
DR BioGRID-ORCS; 26901; 26 hits in 72 CRISPR screens.
DR ChiTaRS; Ss18l2; mouse.
DR PRO; PR:Q9D174; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q9D174; protein.
DR Bgee; ENSMUSG00000032526; Expressed in cardiac muscle of left ventricle and 282 other tissues.
DR ExpressionAtlas; Q9D174; baseline and differential.
DR Genevisible; Q9D174; MM.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR044779; SS18.
DR InterPro; IPR007726; SS18_N.
DR PANTHER; PTHR23107; PTHR23107; 1.
DR Pfam; PF05030; SSXT; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..77
FT /note="SS18-like protein 2"
FT /id="PRO_0000181827"
FT MOTIF 50..53
FT /note="SH2-binding"
FT /evidence="ECO:0000255"
SQ SEQUENCE 77 AA; 8873 MW; 3592C9F07E658DAA CRC64;
MSVIFAPDWL RGKAKVNQET IQRLLEENDQ LIRCIVEYQN KGRANECVQY QHVLHRNLIY
LATIADANTS SLTKAVE
