ID   S20AB_DANRE             Reviewed;         665 AA.
AC   Q6PFM1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Sodium-dependent phosphate transporter 1-B;
DE   AltName: Full=Solute carrier family 20 member 1-B;
GN   Name=slc20a1b; Synonyms=slc20a1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sodium-phosphate symporter which plays a fundamental
CC       housekeeping role in phosphate transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000305}.
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DR   EMBL; BC057497; AAH57497.1; -; mRNA.
DR   RefSeq; NP_997753.1; NM_212588.1.
DR   AlphaFoldDB; Q6PFM1; -.
DR   SMR; Q6PFM1; -.
DR   STRING; 7955.ENSDARP00000039968; -.
DR   PaxDb; Q6PFM1; -.
DR   GeneID; 321541; -.
DR   KEGG; dre:321541; -.
DR   CTD; 321541; -.
DR   ZFIN; ZDB-GENE-030131-260; slc20a1b.
DR   eggNOG; KOG2493; Eukaryota.
DR   InParanoid; Q6PFM1; -.
DR   OrthoDB; 712010at2759; -.
DR   PhylomeDB; Q6PFM1; -.
DR   Reactome; R-DRE-427652; Sodium-coupled phosphate cotransporters.
DR   ChiTaRS; slc20a1b; zebrafish.
DR   PRO; PR:Q6PFM1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PTHR11101; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Phosphate transport; Reference proteome; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..665
FT                   /note="Sodium-dependent phosphate transporter 1-B"
FT                   /id="PRO_0000080775"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        499..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        548..568
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        588..608
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        638..658
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          294..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..342
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   665 AA;  72063 MW;  00C49A8D3CF6D589 CRC64;
     MVSTTLATIT IMSTLVGYTT GPLTDYMWLL IVGFIIAFVL AFSVGANDVA NSFGTAVGSG
     VVTLRQACIL ASIFETLGSV LLGAKVSETI RKGIIDVTMY KDIEHVLMAG SVSAMFGSAV
     WQLAASFLKL PISGTHCIVG ATIGFSLVAK GQQGVKWLEL LRIVASWFLS PLLSGVMSAV
     LFYFVRMFIL QKKDPVPNGL RALPFFYAVT MGINLFSIMF TGAPMLGFDK LPWWGVLLIS
     IGFGIITALI VWFAVCPRLK KKIECEVKSS SPSESPLMEK RELHEAHSPI LKPVPEESSV
     LSSSTPTTPP LPPPEERRVT FDIGDSDDAD QKDCKESDLG GAPKTAHVHF TNGPAHIPSN
     GYSQYHTVHK DSGLYKDLLH KLHLAKVGDC MGEGGDRPIR RNNSYTSYTM AIIGMHGDFK
     PKESEFRASE DGDKEKAGAQ ERKRIRMDSY TSYCNAVAEN GTPEDLGEGE VTLEMVDEDA
     GSSRSSLEED RTDADKPEVS MLFQFLQILT ACFGSFAHGG NDVSNAIGPL VALWLVYESG
     SVISSAPTPI WLLLYGGVGI CVGLWVWGRR VIQTMGRDLT PITPSSGFSI ELASAVTVVV
     ASNIGLPVST THCKVGSVVA VGWLRSRKAV DWRLFRNIFM AWFVTVPISG LISAAIMALF
     NYVIL