ID   S20AB_XENLA             Reviewed;         685 AA.
AC   Q6PB26;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Sodium-dependent phosphate transporter 1-B;
DE   AltName: Full=Solute carrier family 20 member 1-B;
GN   Name=slc20a1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sodium-phosphate symporter which plays a fundamental
CC       housekeeping role in phosphate transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000305}.
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DR   EMBL; BC059957; AAH59957.1; -; mRNA.
DR   RefSeq; NP_001083287.1; NM_001089818.1.
DR   RefSeq; XP_018106332.1; XM_018250843.1.
DR   AlphaFoldDB; Q6PB26; -.
DR   SMR; Q6PB26; -.
DR   DNASU; 398846; -.
DR   GeneID; 398846; -.
DR   KEGG; xla:398846; -.
DR   CTD; 398846; -.
DR   Xenbase; XB-GENE-864924; slc20a1.L.
DR   OMA; MQAFCIA; -.
DR   OrthoDB; 712010at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 398846; Expressed in kidney and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PTHR11101; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Phosphate transport; Reference proteome; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..685
FT                   /note="Sodium-dependent phosphate transporter 1-B"
FT                   /id="PRO_0000080778"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        517..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        565..585
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        606..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        656..676
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          489..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..511
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   685 AA;  74668 MW;  F3356EE3AEF8B3E9 CRC64;
     MESTTAFSAV TSALGIQDVH IMAPYLWMLV LGFVIAFVLA FSVGANDVAN SFGTAVGSGV
     VTLRQACILA SIFETVGSVL LGAKVSETIR KGLIDVTMYN STQELLMAGS ISAMFGSAVW
     QLAASFLKLP ISGTHCIVGA TIGFSLVAKG QQGVKWIELL RIVLSWFISP LLSGIMSALL
     FFFVKKFILC KADPVPNGLR ALPVFYACTI GINLFSIMYT GAPLLGFDKV PLWGIILISV
     GCAVFCALFV WFFVCPRMKR KIECEFKSSP SESPLMNKKN RELHCPILKP DPDNIKLPVD
     GGIVAEVKVP ILDMVTVSRT EERTVTFNMG DCDDPIEKEK LNSMETNIDQ PMNGSVQLAN
     GNHVQFSQTV SNEMNSSGQY QYHTVHKDSG LYKDLLHKLH LAKVGDCMGD SGDKPLRRNN
     SYTSYTMAIC GMPLDSFRNW DAEARPDEAE KLTVHGADGK KRIRMDSYTS YCNAVADAHM
     DVEAEEQEEG CIEDVVTDRK SSSSSLEERH DQDKPEVSLL FQFLQILTAC FGSFAHGGND
     VSNAIGPLVA LYLVYESGDV ATKAATPIWL LLYGGIGICI GLWVWGRRVI QTMGKDLTPI
     TPSSGFSIEL ASALTVVIAS NVGLPISTTH CKVGSVVSVG WLRSKKAVDW RLFRNIFLAW
     FVTVPISGLI SAGIMALFKY AILKV