ID   S247A_DANRE             Reviewed;         294 AA.
AC   Q1ECW7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Solute carrier family 25 member 47-A;
DE   AltName: Full=Hepatocellular carcinoma down-regulated mitochondrial carrier homolog A;
GN   Name=slc25a47a; Synonyms=hdmcpa; ORFNames=zgc:136752;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; BC117643; AAI17644.1; -; mRNA.
DR   RefSeq; NP_001038779.1; NM_001045314.1.
DR   AlphaFoldDB; Q1ECW7; -.
DR   SMR; Q1ECW7; -.
DR   STRING; 7955.ENSDARP00000078311; -.
DR   PaxDb; Q1ECW7; -.
DR   PRIDE; Q1ECW7; -.
DR   Ensembl; ENSDART00000083876; ENSDARP00000078311; ENSDARG00000059923.
DR   GeneID; 724009; -.
DR   KEGG; dre:724009; -.
DR   CTD; 724009; -.
DR   ZFIN; ZDB-GENE-060616-266; slc25a47a.
DR   eggNOG; KOG0762; Eukaryota.
DR   GeneTree; ENSGT00940000159694; -.
DR   HOGENOM; CLU_015166_16_1_1; -.
DR   InParanoid; Q1ECW7; -.
DR   OMA; HCITETV; -.
DR   OrthoDB; 1072378at2759; -.
DR   PhylomeDB; Q1ECW7; -.
DR   TreeFam; TF351739; -.
DR   PRO; PR:Q1ECW7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 20.
DR   Bgee; ENSDARG00000059923; Expressed in muscle tissue and 18 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR002067; Mit_carrier.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00926; MITOCARRIER.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..294
FT                   /note="Solute carrier family 25 member 47-A"
FT                   /id="PRO_0000291782"
FT   TRANSMEM        3..23
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          4..83
FT                   /note="Solcar 1"
FT   REPEAT          95..189
FT                   /note="Solcar 2"
FT   REPEAT          198..286
FT                   /note="Solcar 3"
SQ   SEQUENCE   294 AA;  32158 MW;  C3742EA7BEAC6CA6 CRC64;
     MHFADFLAGS FGGACGVAVG YPLDTVKVRI QTQKQFTGIW QCIVLTIRKE GVHGFFKGMF
     LPITTISMTS SVVFGTYRNC LQALSYIRKA ENTKLDVFMS GLAGGVAQVS VMSPGDIVKV
     RLQCQTESRH SVNPKYSVKP KYSGPIHCLL SICREQGLSG LYRGALPLAL RDGPSFATYF
     LTYHTLCARL TPDGQKEPEW TVVLLSGGVA GMSGWAVGTP MDVIKARLQM DGVRGQRRYR
     GLLHCLTVTT RTEGLGVFFR SLGINCLRAF PVNMVVFAVY EVSVRVLRSA PLVS