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S247B_DANRE
ID   S247B_DANRE             Reviewed;         288 AA.
AC   A4QNX2;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Solute carrier family 25 member 47-B;
DE   AltName: Full=Hepatocellular carcinoma down-regulated mitochondrial carrier homolog B;
GN   Name=slc25a47b; Synonyms=hdmcpb; ORFNames=zgc:162249;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB; TISSUE=Egg;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; BC139556; AAI39557.1; -; mRNA.
DR   RefSeq; NP_001083050.1; NM_001089581.1.
DR   AlphaFoldDB; A4QNX2; -.
DR   SMR; A4QNX2; -.
DR   STRING; 7955.ENSDARP00000105896; -.
DR   GeneID; 100006442; -.
DR   KEGG; dre:100006442; -.
DR   CTD; 100006442; -.
DR   ZFIN; ZDB-GENE-070424-85; slc25a47b.
DR   eggNOG; KOG0758; Eukaryota.
DR   InParanoid; A4QNX2; -.
DR   OrthoDB; 1072378at2759; -.
DR   PhylomeDB; A4QNX2; -.
DR   PRO; PR:A4QNX2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR002067; Mit_carrier.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00926; MITOCARRIER.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..288
FT                   /note="Solute carrier family 25 member 47-B"
FT                   /id="PRO_0000291783"
FT   TRANSMEM        3..23
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..75
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1..83
FT                   /note="Solcar 1"
FT   REPEAT          99..191
FT                   /note="Solcar 2"
FT   REPEAT          199..286
FT                   /note="Solcar 3"
SQ   SEQUENCE   288 AA;  31537 MW;  DF5DBBC933D4F7A7 CRC64;
     MHLADFLAGS VGGAFGVAVG YPLDTVKVRL QTQTGYSGFW QCVRKTCRNE GLQGFYRGMS
     MPISTVSISS SLVFGTYRNI LQFLHQLQHR SAGEPHHKAH IFLAGFTGGV TQVLVMAPAD
     IVKVRLQCQT EPVQHISQES SSKYRGPVQC LLRIARDEGL LGLYKGSAAL ALRDGPSFAT
     YFLTYNTICE ILTTENQRPG WPVVLLAGGV SGMCGWAVGT PMDVIKSRLQ VDGVSGRRYR
     GFLHCITHSV RTEGSGVLFR GLTVNCIRAF PVNMSVFAMY EAVVRLLR
 
 
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