S247B_DANRE
ID S247B_DANRE Reviewed; 288 AA.
AC A4QNX2;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Solute carrier family 25 member 47-B;
DE AltName: Full=Hepatocellular carcinoma down-regulated mitochondrial carrier homolog B;
GN Name=slc25a47b; Synonyms=hdmcpb; ORFNames=zgc:162249;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=AB; TISSUE=Egg;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; BC139556; AAI39557.1; -; mRNA.
DR RefSeq; NP_001083050.1; NM_001089581.1.
DR AlphaFoldDB; A4QNX2; -.
DR SMR; A4QNX2; -.
DR STRING; 7955.ENSDARP00000105896; -.
DR GeneID; 100006442; -.
DR KEGG; dre:100006442; -.
DR CTD; 100006442; -.
DR ZFIN; ZDB-GENE-070424-85; slc25a47b.
DR eggNOG; KOG0758; Eukaryota.
DR InParanoid; A4QNX2; -.
DR OrthoDB; 1072378at2759; -.
DR PhylomeDB; A4QNX2; -.
DR PRO; PR:A4QNX2; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..288
FT /note="Solute carrier family 25 member 47-B"
FT /id="PRO_0000291783"
FT TRANSMEM 3..23
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..75
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 1..83
FT /note="Solcar 1"
FT REPEAT 99..191
FT /note="Solcar 2"
FT REPEAT 199..286
FT /note="Solcar 3"
SQ SEQUENCE 288 AA; 31537 MW; DF5DBBC933D4F7A7 CRC64;
MHLADFLAGS VGGAFGVAVG YPLDTVKVRL QTQTGYSGFW QCVRKTCRNE GLQGFYRGMS
MPISTVSISS SLVFGTYRNI LQFLHQLQHR SAGEPHHKAH IFLAGFTGGV TQVLVMAPAD
IVKVRLQCQT EPVQHISQES SSKYRGPVQC LLRIARDEGL LGLYKGSAAL ALRDGPSFAT
YFLTYNTICE ILTTENQRPG WPVVLLAGGV SGMCGWAVGT PMDVIKSRLQ VDGVSGRRYR
GFLHCITHSV RTEGSGVLFR GLTVNCIRAF PVNMSVFAMY EAVVRLLR