BEND4_MOUSE
ID BEND4_MOUSE Reviewed; 541 AA.
AC P86174;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 2.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=BEN domain-containing protein 4 {ECO:0000312|MGI:MGI:3648414};
GN Name=Bend4 {ECO:0000312|MGI:MGI:3648414};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AC122562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS51512.1; -.
DR RefSeq; NP_001158278.1; NM_001164806.1.
DR AlphaFoldDB; P86174; -.
DR SMR; P86174; -.
DR BioGRID; 578765; 1.
DR STRING; 10090.ENSMUSP00000132684; -.
DR iPTMnet; P86174; -.
DR PhosphoSitePlus; P86174; -.
DR MaxQB; P86174; -.
DR PaxDb; P86174; -.
DR PRIDE; P86174; -.
DR ProteomicsDB; 273667; -.
DR Antibodypedia; 23689; 127 antibodies from 26 providers.
DR Ensembl; ENSMUST00000169190; ENSMUSP00000132684; ENSMUSG00000092060.
DR Ensembl; ENSMUST00000201972; ENSMUSP00000144639; ENSMUSG00000092060.
DR GeneID; 666938; -.
DR KEGG; mmu:666938; -.
DR UCSC; uc012dws.1; mouse.
DR CTD; 389206; -.
DR MGI; MGI:3648414; Bend4.
DR VEuPathDB; HostDB:ENSMUSG00000092060; -.
DR eggNOG; ENOG502QUMQ; Eukaryota.
DR GeneTree; ENSGT00390000014963; -.
DR HOGENOM; CLU_048382_1_0_1; -.
DR InParanoid; P86174; -.
DR OMA; PCETRPS; -.
DR OrthoDB; 538137at2759; -.
DR PhylomeDB; P86174; -.
DR TreeFam; TF332060; -.
DR BioGRID-ORCS; 666938; 3 hits in 71 CRISPR screens.
DR ChiTaRS; Bend4; mouse.
DR PRO; PR:P86174; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; P86174; protein.
DR Bgee; ENSMUSG00000092060; Expressed in lumbar dorsal root ganglion and 164 other tissues.
DR ExpressionAtlas; P86174; baseline and differential.
DR Genevisible; P86174; MM.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR InterPro; IPR018379; BEN_domain.
DR InterPro; IPR038950; BEND4.
DR PANTHER; PTHR35082; PTHR35082; 1.
DR Pfam; PF10523; BEN; 1.
DR SMART; SM01025; BEN; 1.
DR PROSITE; PS51457; BEN; 1.
PE 4: Predicted;
KW Coiled coil; Reference proteome.
FT CHAIN 1..541
FT /note="BEN domain-containing protein 4"
FT /id="PRO_0000364182"
FT DOMAIN 398..506
FT /note="BEN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00784"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 333..360
FT /evidence="ECO:0000255"
FT COMPBIAS 51..69
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..133
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 58721 MW; 5CE6CA986EA84E02 CRC64;
MEPEMQAAEE GPSAPRIYKQ RGPYSVLKTF PSRRPALAKR YDRPSLLELS PARPSPLPPP
PPPPPFASLA AVPISSSEPP PFPTQPSYPA GSGRAPAAAA ASSSSPSCTP AAPPGHPRTP
APPPPPPPPL AAPAASSSSS FAAVVRYGPG PATGACSSGA GSDGASLELS AESRMILDAF
AQQCSRVLSL LNCGGKLLDS NHSQSMISCV KQEGSSYNER QDQCHIVKGV QSQTSDNIDI
EMQYMQRKQQ TSAFLRVFTD SLQNYLLSGS FPTPNTSSAS EYGHLADVDP LSASPVHTLG
GWTSPATSES HGHPSSSTLP EEEEEEEEEG YCPRCQELEQ EVISLQQENE ELRRKLESIP
VPCQTVLDYL KTVLLHHNQL LPQPAEQPTE GSKQLLNNYP VYITSKQWDE AVNSSKKDGR
RLLRYLIRFV FTTDELKYSC GLGKRKRSVQ SGETGPERRP LDPVKVTCLR EFIRMHCTSN
PDWWMPSEEQ INKVFSDAVG HARQGRAVGT FLHNGGSFYE GMDHQASQDE VFSKTQDGSG
D