S2535_DANRE
ID S2535_DANRE Reviewed; 298 AA.
AC A3KPP4; B7ZVE4;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Solute carrier family 25 member 35;
GN Name=slc25a35; ORFNames=si:ch211-268m12.5;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; BX276102; CAM46934.1; -; Genomic_DNA.
DR EMBL; BC171554; AAI71554.1; -; mRNA.
DR EMBL; BC171721; AAI71721.1; -; mRNA.
DR RefSeq; NP_001092917.1; NM_001099447.1.
DR AlphaFoldDB; A3KPP4; -.
DR SMR; A3KPP4; -.
DR STRING; 7955.ENSDARP00000003308; -.
DR PaxDb; A3KPP4; -.
DR Ensembl; ENSDART00000163048; ENSDARP00000140871; ENSDARG00000102783.
DR GeneID; 557185; -.
DR KEGG; dre:557185; -.
DR CTD; 399512; -.
DR ZFIN; ZDB-GENE-060526-142; slc25a35.
DR eggNOG; KOG0755; Eukaryota.
DR GeneTree; ENSGT00940000160771; -.
DR HOGENOM; CLU_015166_14_3_1; -.
DR InParanoid; A3KPP4; -.
DR OMA; VMSRMYN; -.
DR OrthoDB; 1013743at2759; -.
DR PhylomeDB; A3KPP4; -.
DR TreeFam; TF324506; -.
DR PRO; PR:A3KPP4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000102783; Expressed in retina and 17 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..298
FT /note="Solute carrier family 25 member 35"
FT /id="PRO_0000291796"
FT TRANSMEM 38..58
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..118
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..189
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 1..90
FT /note="Solcar 1"
FT REPEAT 99..192
FT /note="Solcar 2"
FT REPEAT 202..293
FT /note="Solcar 3"
SQ SEQUENCE 298 AA; 32284 MW; BD5944431B01DF94 CRC64;
MDFILGGVAA CGACFFTNPL EVVKTRMQLQ GELKSRGTYQ VYYRNVFHAF YTIGKIDGLA
GLQKGLVPGL VYQFFMNGVR LGSYALTESL GYIHTDGRVS ATKSTVSGAI AGVVGAVMGS
PIYLVKTHLQ SQSTSSIAVG HQYKHRGMTN ALFAIHKQHG ILGLWRGASA AIPRVSVGSA
AQLATFSASK EMVNDLQVFS EGSWLIALSA GMISSVVVVL AMTPFDVVST RLYNQPVDHL
GKGMLYRGFV DCFSKTLKKE GMTGLYKGLG ASYFRLGPHT ILSLLFWNEL RCLHQSYS
