ID   S2536_CHICK             Reviewed;         313 AA.
AC   Q5ZKP7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Solute carrier family 25 member 36;
GN   Name=SLC25A36; ORFNames=RCJMB04_9m7;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Mitochondrial transporter that imports/exports pyrimidine
CC       nucleotides into and from mitochondria. Transports preferentially
CC       cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by
CC       uniport and antiport mechanism. {ECO:0000250|UniProtKB:Q96CQ1}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q96CQ1}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; AJ720037; CAG31696.1; -; mRNA.
DR   RefSeq; NP_001007961.1; NM_001007960.1.
DR   AlphaFoldDB; Q5ZKP7; -.
DR   SMR; Q5ZKP7; -.
DR   STRING; 9031.ENSGALP00000008458; -.
DR   PaxDb; Q5ZKP7; -.
DR   Ensembl; ENSGALT00000008472; ENSGALP00000008458; ENSGALG00000005283.
DR   GeneID; 424817; -.
DR   KEGG; gga:424817; -.
DR   CTD; 55186; -.
DR   VEuPathDB; HostDB:geneid_424817; -.
DR   eggNOG; KOG0757; Eukaryota.
DR   GeneTree; ENSGT00940000154369; -.
DR   HOGENOM; CLU_015166_6_0_1; -.
DR   InParanoid; Q5ZKP7; -.
DR   OMA; HVHEGWR; -.
DR   OrthoDB; 1372287at2759; -.
DR   PhylomeDB; Q5ZKP7; -.
DR   TreeFam; TF314220; -.
DR   PRO; PR:Q5ZKP7; -.
DR   Proteomes; UP000000539; Chromosome 9.
DR   Bgee; ENSGALG00000005283; Expressed in spermatid and 12 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0015218; F:pyrimidine nucleotide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IBA:GO_Central.
DR   GO; GO:1990519; P:pyrimidine nucleotide import into mitochondrion; IBA:GO_Central.
DR   Gene3D; 1.50.40.10; -; 2.
DR   InterPro; IPR002067; Mit_carrier.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00926; MITOCARRIER.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..313
FT                   /note="Solute carrier family 25 member 36"
FT                   /id="PRO_0000291799"
FT   TRANSMEM        7..27
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..57
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          4..110
FT                   /note="Solcar 1"
FT   REPEAT          118..205
FT                   /note="Solcar 2"
FT   REPEAT          226..310
FT                   /note="Solcar 3"
SQ   SEQUENCE   313 AA;  34557 MW;  BA653E2132E4B006 CRC64;
     MSQRDTLVHL FAGGCGGTVG AILTCPLEVV KTRLQSSSVT LYISEVHLNT VNGASVNRVT
     RVSPGPLHCL KMILQKEGPR SLFRGLGPNL VGVAPSRAIY FAAYSNCKEK LNNIFNPDST
     QVHMISAGVA GFTAITMTNP IWLVKTRLQL DARNRGEKRM SAFECVRKVY RSDGIKGFYR
     GMSASYAGIS ETVIHFVIYE SIKRKLLEHK TASAMDSEDE SAKEASDFVG MMMAAATSKT
     CATSIAYPHE VVRTRLREEG TKYRSFFQTL SLLVREEGYG SLYRGLTTHL VRQIPNTAIM
     MSTYEVVVYL LDG