BEND5_XENLA
ID BEND5_XENLA Reviewed; 393 AA.
AC Q3B8D4;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=BEN domain-containing protein 5;
GN Name=bend5;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as a transcriptional repressor.
CC {ECO:0000250|UniProtKB:Q7L4P6}.
CC -!- DOMAIN: The BEN domain mediates DNA-binding.
CC {ECO:0000250|UniProtKB:Q7L4P6}.
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DR EMBL; BC106563; AAI06564.1; -; mRNA.
DR RefSeq; NP_001089788.1; NM_001096319.1.
DR AlphaFoldDB; Q3B8D4; -.
DR SMR; Q3B8D4; -.
DR PRIDE; Q3B8D4; -.
DR DNASU; 734853; -.
DR GeneID; 734853; -.
DR KEGG; xla:734853; -.
DR CTD; 734853; -.
DR Xenbase; XB-GENE-940889; bend5.S.
DR OrthoDB; 727836at2759; -.
DR Proteomes; UP000186698; Chromosome 4S.
DR Bgee; 734853; Expressed in testis and 18 other tissues.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR018379; BEN_domain.
DR InterPro; IPR040391; BEND5.
DR PANTHER; PTHR14628; PTHR14628; 1.
DR Pfam; PF10523; BEN; 1.
DR SMART; SM01025; BEN; 1.
DR PROSITE; PS51457; BEN; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..393
FT /note="BEN domain-containing protein 5"
FT /id="PRO_0000274281"
FT DOMAIN 274..380
FT /note="BEN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00784"
FT COILED 169..212
FT /evidence="ECO:0000255"
SQ SEQUENCE 393 AA; 45882 MW; 0EDFA126222547E6 CRC64;
MFAFVRFLED NVCYALPATR VREFHPHSTE DFDSRRVYAV YRSLEEEAGF PGAPQQAQIL
ALAENKTDLE NRVMQKKIKI PKISLNYSEQ PWEYKDYEDE EDSEFRHFKR ADGRKQVESP
HKSIEAVVAR LEKQSFIGPS HNTRCDEVFS EPFHSVGHMD RLEAAVVPRV LYEELLRSYQ
QQQQEMKHIQ HELERTRKQL VQQAKKLKDY GSLVTEVKEL RVLNRRLQDV LLLRLGSGPT
IELQIDKSDY CDPEPEPEPE PEIQKISNEE VHLGSGVWVN EEKWHQLQAT QGDSKYTKNL
AVMIWGTDVL KNRSVTGVAT KKKKDAVPKP PLSPHKLSVV RECMYDRIAR ETMDENEIAQ
RLSKVNKYIC EKIMDINKSC KNEERREAKY NVQ