ID   S2543_DANRE             Reviewed;         345 AA.
AC   Q5U3V7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Solute carrier family 25 member 43;
GN   Name=slc25a43; ORFNames=zgc:101590;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; BC085377; AAH85377.1; -; mRNA.
DR   RefSeq; NP_001004497.2; NM_001004497.2.
DR   AlphaFoldDB; Q5U3V7; -.
DR   SMR; Q5U3V7; -.
DR   STRING; 7955.ENSDARP00000104989; -.
DR   PaxDb; Q5U3V7; -.
DR   GeneID; 796731; -.
DR   KEGG; dre:796731; -.
DR   CTD; 203427; -.
DR   ZFIN; ZDB-GENE-030616-69; slc25a43.
DR   eggNOG; KOG0752; Eukaryota.
DR   InParanoid; Q5U3V7; -.
DR   OrthoDB; 1253450at2759; -.
DR   PhylomeDB; Q5U3V7; -.
DR   PRO; PR:Q5U3V7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR002067; Mit_carrier.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00926; MITOCARRIER.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..345
FT                   /note="Solute carrier family 25 member 43"
FT                   /id="PRO_0000291825"
FT   TRANSMEM        16..36
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        261..281
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          11..100
FT                   /note="Solcar 1"
FT   REPEAT          104..195
FT                   /note="Solcar 2"
FT   REPEAT          199..297
FT                   /note="Solcar 3"
SQ   SEQUENCE   345 AA;  38518 MW;  4079101CF19C7086 CRC64;
     MATVKKDARL TSSQSLMCVG FAGIFSKTVT SPLEVVKILS QVGTFHCKRG FLHSFVLICQ
     NEGLRAFWKG NMVSCLRLFP YSAIHLATYK NIVNLHIDEL GDISQWRAIV AGGLAGISAA
     LATYPLEVVE TRLIAQNCQE PTYRGLLHSL SVIYRNEGLQ ALYRGFSLTV LGAVPFSVGC
     YAVYINLDKL WQERHVRFTS LQNFINGCLA AGVAQTLSFP FETVKKKMQA QSLVLPHCGG
     VDVHFNGMAD CFRQVIKNKG VMALWSGLTA NMVKIVPYFG LLFSCFEMCK QVCLYRNGYI
     ISPPSYKLKP GVDQSLGPYE LQEFKRYLRN RKSHKAQSSS IGNRW