ID   S2548_DANRE             Reviewed;         309 AA.
AC   Q6DHS9;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Solute carrier family 25 member 48;
GN   Name=slc25a48; ORFNames=zgc:92090;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000305}.
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DR   EMBL; BC075888; AAH75888.1; -; mRNA.
DR   RefSeq; NP_001002367.1; NM_001002367.1.
DR   AlphaFoldDB; Q6DHS9; -.
DR   SMR; Q6DHS9; -.
DR   STRING; 7955.ENSDARP00000040954; -.
DR   PaxDb; Q6DHS9; -.
DR   Ensembl; ENSDART00000040955; ENSDARP00000040954; ENSDARG00000021250.
DR   GeneID; 436640; -.
DR   KEGG; dre:436640; -.
DR   CTD; 153328; -.
DR   ZFIN; ZDB-GENE-040718-60; slc25a48.
DR   eggNOG; KOG0762; Eukaryota.
DR   GeneTree; ENSGT00940000159354; -.
DR   HOGENOM; CLU_015166_16_1_1; -.
DR   InParanoid; Q6DHS9; -.
DR   OMA; YGVWFLA; -.
DR   OrthoDB; 1072378at2759; -.
DR   PhylomeDB; Q6DHS9; -.
DR   TreeFam; TF351739; -.
DR   PRO; PR:Q6DHS9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 14.
DR   Bgee; ENSDARG00000021250; Expressed in liver and 18 other tissues.
DR   ExpressionAtlas; Q6DHS9; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 1.50.40.10; -; 1.
DR   InterPro; IPR002067; Mit_carrier.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   Pfam; PF00153; Mito_carr; 3.
DR   PRINTS; PR00926; MITOCARRIER.
DR   SUPFAM; SSF103506; SSF103506; 1.
DR   PROSITE; PS50920; SOLCAR; 3.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Repeat; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..309
FT                   /note="Solute carrier family 25 member 48"
FT                   /id="PRO_0000325770"
FT   TRANSMEM        9..29
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..299
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          3..86
FT                   /note="Solcar 1"
FT   REPEAT          99..209
FT                   /note="Solcar 2"
FT   REPEAT          218..305
FT                   /note="Solcar 3"
SQ   SEQUENCE   309 AA;  34107 MW;  54AA0775FBE6EE26 CRC64;
     MTVFQLDDFL AGWIGGASSV IVGHPLDTVK TRLQAGKGYK NTFHCVVTIY KKENVIGFFK
     GLSFPLASIT LYNSMVFGFF SNTQRLISKY RYGDGRHPCS MLDLTVASML TGLVSVGVGA
     PVDLVKIRLQ MQTQPVLAEN FNLAGNGSVP LRSMGIQSQS FYRGPLHCIS TVLQNEGIQG
     LYRGAGAMIL RDIPGYALYF IPYTLFCNWL NPDDNSSPPP CCIWLAGGLA GSISWVTATP
     SDVVKSRLQA DAMHQRKYKG ILHCIMQSYR TEGIHVFFRG ATVNAIRGFP MCATMFLGYE
     LSLQFFRSF