BENK_ACIAD
ID BENK_ACIAD Reviewed; 466 AA.
AC O30513; Q6FCB3;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 2.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Benzoate transport protein;
GN Name=benK; OrderedLocusNames=ACIAD1434;
OS Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=62977;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9294456; DOI=10.1128/jb.179.18.5943-5946.1997;
RA Collier L.S., Nichols N.N., Neidle E.L.;
RT "benK encodes a hydrophobic permease-like protein involved in benzoate
RT degradation by Acinetobacter sp. strain ADP1.";
RL J. Bacteriol. 179:5943-5946(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33305 / BD413 / ADP1;
RX PubMed=15514110; DOI=10.1093/nar/gkh910;
RA Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT a versatile and naturally transformation competent bacterium.";
RL Nucleic Acids Res. 32:5766-5779(2004).
CC -!- FUNCTION: Probable uptake of benzoate.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Aromatic
CC acid:H(+) symporter (AAHS) (TC 2.A.1.15) family. {ECO:0000305}.
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DR EMBL; AF009224; AAC46425.1; -; Genomic_DNA.
DR EMBL; CR543861; CAG68298.1; -; Genomic_DNA.
DR RefSeq; WP_004925503.1; NC_005966.1.
DR AlphaFoldDB; O30513; -.
DR SMR; O30513; -.
DR STRING; 62977.ACIAD1434; -.
DR TCDB; 2.A.1.15.5; the major facilitator superfamily (mfs).
DR EnsemblBacteria; CAG68298; CAG68298; ACIAD1434.
DR GeneID; 45233847; -.
DR KEGG; aci:ACIAD1434; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_46_4_6; -.
DR OMA; LDWTLGN; -.
DR OrthoDB; 1121832at2; -.
DR BioCyc; ASP62977:ACIAD_RS06625-MON; -.
DR Proteomes; UP000000430; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR004746; MFS_AAHS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00895; 2A0115; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..466
FT /note="Benzoate transport protein"
FT /id="PRO_0000050297"
FT TOPO_DOM 1..22
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 23..43
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 44..60
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..93
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..119
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 141..150
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 172..181
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 182..202
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 203..258
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 259..279
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 280..297
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..318
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 319..325
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 347..348
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 370..387
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 409..414
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 415..435
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 436..466
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 199
FT /note="K -> E (in Ref. 1; AAC46425)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 466 AA; 51403 MW; 26422E6283FCF333 CRC64;
MSREINVNQM IDDSKLTPFH WRVIILSTLI IIFDGYDLVI YGVALPLLMK EWAIDPVTAG
FIGSIALFGM MFGALIFGTI ADKLEHLGVS RKKVIAVCII LFSLCTVLCG FSETTTQFSI
FRFLAGVGIG GVMPNVIALV SEYAPKKFKS FFVTLMFSGY AIGGMTAAFL GSILVPLYGW
KIMFMIAGIP LVLLLPLMKV LPESIDYLVR KKKDETVRFI MTKMVPSYQY QPDHVFVLNS
SNQNQAQAPV KMIFQEQRAF STMMFWCSIF MTLIMVYALG NWLPKLMIEA GYNLSKSLIF
LFSLNVGGMI GSILGGYLAD RYNVKFVTMG LLLLGAISLS LLSFQFSSVI LYILIACAGA
ASIGAQIMLL AYMAKFYAPN VRSTGIGWGL GMGRVGAILG PILTGWLLSL QLPHFYNFLA
LSIPAVLGIV TVFLINDRRM YQPEPISPIA NQNDTTTVKV NEAVSH
