S2B24_MOUSE
ID S2B24_MOUSE Reviewed; 112 AA.
AC Q7M747;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Secretoglobin family 2B member 24;
DE AltName: Full=Allergen dI chain C2B;
DE AltName: Full=Androgen-binding protein zeta;
DE AltName: Full=Lacrimal androgen-binding protein zeta;
DE Flags: Precursor;
GN Name=Scgb2b24; Synonyms=Abpz;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=12406855; DOI=10.1164/rccm.200204-285oc;
RA Reynolds S.D., Reynolds P.R., Pryhuber G.S., Finder J.D., Stripp B.R.;
RT "Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse
RT and human airways.";
RL Am. J. Respir. Crit. Care Med. 166:1498-1509(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=Swiss Webster; TISSUE=Lacrimal gland;
RX PubMed=15623751; DOI=10.1167/iovs.04-0216;
RA Remington S.G., Nelson J.D.;
RT "Secretoglobins: sexually dimorphic expression of androgen-binding protein
RT mRNA in mouse lacrimal glands.";
RL Invest. Ophthalmol. Vis. Sci. 46:31-38(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in lacrimal gland, at higher level in
CC males than females. {ECO:0000269|PubMed:15623751}.
CC -!- SIMILARITY: Belongs to the secretoglobin family. {ECO:0000305}.
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DR EMBL; BK000194; DAA00351.1; -; mRNA.
DR EMBL; AY370635; AAQ72535.1; -; mRNA.
DR EMBL; BC115602; AAI15603.1; -; mRNA.
DR EMBL; BC115603; AAI15604.1; -; mRNA.
DR EMBL; BX537299; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS21132.1; -.
DR RefSeq; NP_803229.1; NM_177446.2.
DR AlphaFoldDB; Q7M747; -.
DR SMR; Q7M747; -.
DR STRING; 10090.ENSMUSP00000052456; -.
DR iPTMnet; Q7M747; -.
DR PhosphoSitePlus; Q7M747; -.
DR PaxDb; Q7M747; -.
DR PRIDE; Q7M747; -.
DR ProteomicsDB; 253380; -.
DR DNASU; 233090; -.
DR Ensembl; ENSMUST00000055444; ENSMUSP00000052456; ENSMUSG00000046438.
DR GeneID; 233090; -.
DR KEGG; mmu:233090; -.
DR UCSC; uc009gim.1; mouse.
DR CTD; 233090; -.
DR MGI; MGI:2655741; Scgb2b24.
DR VEuPathDB; HostDB:ENSMUSG00000046438; -.
DR eggNOG; ENOG502RU0W; Eukaryota.
DR GeneTree; ENSGT00900000141269; -.
DR HOGENOM; CLU_169363_0_0_1; -.
DR InParanoid; Q7M747; -.
DR OMA; IGRIQDC; -.
DR OrthoDB; 1533749at2759; -.
DR PhylomeDB; Q7M747; -.
DR TreeFam; TF339762; -.
DR BioGRID-ORCS; 233090; 1 hit in 73 CRISPR screens.
DR PRO; PR:Q7M747; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q7M747; protein.
DR Bgee; ENSMUSG00000046438; Expressed in lip and 3 other tissues.
DR ExpressionAtlas; Q7M747; baseline and differential.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR CDD; cd00633; Secretoglobin; 1.
DR InterPro; IPR015332; CH2-like.
DR InterPro; IPR016126; Secretoglobin.
DR InterPro; IPR035960; Secretoglobin_sf.
DR PANTHER; PTHR31708; PTHR31708; 1.
DR Pfam; PF09252; Feld-I_B; 1.
DR SUPFAM; SSF48201; SSF48201; 1.
DR PROSITE; PS51311; SCGB; 1.
PE 2: Evidence at transcript level;
KW Allergen; Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..112
FT /note="Secretoglobin family 2B member 24"
FT /id="PRO_0000342376"
SQ SEQUENCE 112 AA; 12535 MW; E6E778F10DAB58B1 CRC64;
MKGTLLLLAL LMIGELGFHT TEACVPFFAG YAGVISGSRL WLYHELSAFN GTPKETVAYE
KIQDCYKEQG VKSQTLEPQI LASILVTPEC LQYYSEETFT KIKDALKKIS QH
