ID   S2_BPMU                 Reviewed;         328 AA.
AC   P0DJY6;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   14-MAY-2014, sequence version 1.
DT   23-FEB-2022, entry version 18.
DE   RecName: Full=Tail fiber protein S';
DE   AltName: Full=Gene product S';
DE            Short=gpS';
GN   Name=S'; OrderedLocusNames=Mup52;
OS   Escherichia phage Mu (Bacteriophage Mu).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Muvirus.
OX   NCBI_TaxID=10677;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11922669; DOI=10.1006/jmbi.2002.5437;
RA   Morgan G.J., Hatfull G.F., Casjens S., Hendrix R.W.;
RT   "Bacteriophage Mu genome sequence: analysis and comparison with Mu-like
RT   prophages in Haemophilus, Neisseria and Deinococcus.";
RL   J. Mol. Biol. 317:337-359(2002).
RN   [2]
RP   INDUCTION.
RX   PubMed=8293968; DOI=10.1093/genetics/135.3.619;
RA   Chiang L.W., Howe M.M.;
RT   "Mutational analysis of a C-dependent late promoter of bacteriophage Mu.";
RL   Genetics 135:619-629(1993).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=8599204; DOI=10.1006/viro.1996.0107;
RA   Grimaud R.;
RT   "Bacteriophage Mu head assembly.";
RL   Virology 217:200-210(1996).
CC   -!- FUNCTION: Component of the tail fiber that acts as receptor binding
CC       protein. Binds to the primary receptor, thereby determining the host
CC       range. Two alternate tail fiber S and S' proteins are encoded extending
CC       the host range of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:8599204}. Host
CC       cytoplasm {ECO:0000305|PubMed:8599204}. Note=Tail fiber. {ECO:0000305}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       Expression of late genes is activated by the viral late transcription
CC       activator C. Expressed alternatively with tail fiber protein S'
CC       (associated with tail fiber assembly protein U'). The switch from S-U
CC       to S'-U' is performed through inversion of a DNA segment called G by
CC       the phage invertase protein Gin. {ECO:0000269|PubMed:8293968}.
CC   -!- MISCELLANEOUS: The orientation of the G segment is defined as G+ and
CC       G-. G+ orientation provides S-U fibers whereas G- provides S'-U'
CC       fibers. S-U and S'-U' dont have the same host range (e.g. respectively
CC       E.coli and C.freundii).
CC   -!- SIMILARITY: Belongs to the caudovirales tail fiber protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF083977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_602303.1; NC_000929.1.
DR   GeneID; 2636274; -.
DR   KEGG; vg:2636274; -.
DR   Proteomes; UP000002611; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098024; C:virus tail, fiber; IEA:UniProtKB-KW.
DR   GO; GO:0098671; P:adhesion receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0098678; P:viral tropism switching; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Host-virus interaction; Late protein; Reference proteome;
KW   Viral attachment to host adhesion receptor; Viral attachment to host cell;
KW   Viral receptor tropism switching; Viral tail fiber protein;
KW   Viral tail protein; Virion; Virus entry into host cell.
FT   CHAIN           1..328
FT                   /note="Tail fiber protein S'"
FT                   /id="PRO_0000429065"
SQ   SEQUENCE   328 AA;  35355 MW;  E55AE4F3BF535234 CRC64;
     MPKSTIIQNL GLQETVNQAS GALQQNQNGA DIPGKDTFTK NIGACRAYSA WLNIGGDSQV
     WTTAQFISWL ESQGAFNHPY WMCKGSWAYA NNKVITDTGC GNICLAGAVV EVIGTRGAMT
     IRVTTPSTSS GGGITNAQFT YINHGDAYAP GWRRDYNTKN QQPAFALGQT GSTVGNDKAV
     GWNWNSGVYN ANIGGASTLI LHFNMNTGSC PAVQFRVNYR NGGIFYRSAR DGYGFEADWS
     EIYTTTRKPS AGDVGAYTQA ECNSRFITGI RLGGLSSVQT WNGPGWSDRS GYVVTGSVNG
     NRDELIDTTQ ARPIQYCING TWYNAGSI