ID   S35A5_PONAB             Reviewed;         424 AA.
AC   Q5R4D7;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Probable UDP-sugar transporter protein SLC35A5;
DE   AltName: Full=Solute carrier family 35 member A5;
GN   Name=SLC35A5;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35A
CC       subfamily. {ECO:0000305}.
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DR   EMBL; CR861314; CAH93379.1; -; mRNA.
DR   RefSeq; NP_001126985.1; NM_001133513.1.
DR   AlphaFoldDB; Q5R4D7; -.
DR   SMR; Q5R4D7; -.
DR   STRING; 9601.ENSPPYP00000015147; -.
DR   PRIDE; Q5R4D7; -.
DR   GeneID; 100174008; -.
DR   KEGG; pon:100174008; -.
DR   CTD; 55032; -.
DR   eggNOG; KOG2234; Eukaryota.
DR   InParanoid; Q5R4D7; -.
DR   OrthoDB; 703674at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR007271; Nuc_sug_transpt.
DR   PANTHER; PTHR10231; PTHR10231; 1.
DR   Pfam; PF04142; Nuc_sug_transp; 1.
DR   PIRSF; PIRSF005799; UDP-gal_transpt; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..424
FT                   /note="Probable UDP-sugar transporter protein SLC35A5"
FT                   /id="PRO_0000309357"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          395..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..424
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         394
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BS91"
FT   MOD_RES         416
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BS91"
FT   MOD_RES         419
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BS91"
FT   CARBOHYD        204
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   424 AA;  48419 MW;  8EE732E323077D2E CRC64;
     MEKQCCSHPV ICSLSTMYTF LLGAIFIALS SSRILLVKYS ANEENKYDYL PTTANVCSEL
     VKLVFCVLVS FCVIKKDHQS RNLKYASWKE FSNFMKWSIP AFLYFLDNLI VFYVLSYLQP
     AMAVIFSNFS IITTALLFRI VLKRRLNWIQ WASLLILFLS IVALTAGTKT LQHNLAGHGF
     HHDAFFSPSN SCLLFRSECP RKDNCTAKEW TFPEAKWNTT ARVFSHIRLG MGHVLIIVQC
     FISSMANIYN EKILKEGNQL AESIFIQNSK LYFFGILFNG LTLGLQRSNR DQIKNCGFFY
     GHNAFSVALI FVTAFQGLSV AFILKFLDNM FHVLMAQVTT VIITTVSVLV FDFRPSLEFF
     LEAPSVLLSI FIYNASKPQG PEYAPRQERI RDLSGNLWER SSGDGEELER LTKPKSDESD
     EDTF