ID   S35A5_XENLA             Reviewed;         413 AA.
AC   Q6DCG9;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Probable UDP-sugar transporter protein SLC35A5;
DE   AltName: Full=Solute carrier family 35 member A5;
GN   Name=slc35a5;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35A
CC       subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC078070; AAH78070.1; -; mRNA.
DR   RefSeq; NP_001087145.1; NM_001093676.1.
DR   AlphaFoldDB; Q6DCG9; -.
DR   SMR; Q6DCG9; -.
DR   DNASU; 447034; -.
DR   GeneID; 447034; -.
DR   KEGG; xla:447034; -.
DR   CTD; 447034; -.
DR   Xenbase; XB-GENE-6254575; slc35a5.S.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 447034; Expressed in blastula and 19 other tissues.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR007271; Nuc_sug_transpt.
DR   PANTHER; PTHR10231; PTHR10231; 1.
DR   Pfam; PF04142; Nuc_sug_transp; 1.
DR   PIRSF; PIRSF005799; UDP-gal_transpt; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..413
FT                   /note="Probable UDP-sugar transporter protein SLC35A5"
FT                   /id="PRO_0000309359"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        167
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   413 AA;  46978 MW;  23C0EED67AA0F535 CRC64;
     MSYKCCLNRA WLSRSHLHTF LLGFTFVSLG SSRLLLVKFS ANEDNKYDYV PATVNVCAEA
     VKLLFCMAMS VRIIMTERRS FRCHASLKHF CQYMKWAVPA FLYFLDNLII FYVLAYLQPA
     MAVLLSNFVI ITTAVFFRLI LKRQLSCVQW ASLVILFLSI MGLTSRNDTA HHEVSVDVHH
     HLFHSAPSNS CTYLNKPDTE AHTVSLKAIA NFQFLHLGLG HFLILLQCVI SALANIYNEK
     ILKEGEQMSE SIFIQNSKLY VFGVFFNGLT LVLHDEYFSK IKSCGFFYGH NGFSVALIFT
     TAFVGLSVAF ILKFRDNMFH VLTAQITTVI ITIVSYFVFS FKPSLDFFLE APVVLLSIFI
     YNASRITESS GTTKREKLKI INGDVWERSN GDGQELEKLT AANEDSETDE EIF