S35B1_CHICK
ID S35B1_CHICK Reviewed; 325 AA.
AC Q8AWB6;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Solute carrier family 35 member B1;
DE AltName: Full=Endoplasmic reticulum nucleotide sugar transporter 1;
GN Name=SLC35B1; Synonyms=ERNST1;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND GENE FAMILY.
RX PubMed=12770764; DOI=10.1016/s0300-9084(03)00046-4;
RA Martinez-Duncker I., Mollicone R., Codogno P., Oriol R.;
RT "The nucleotide-sugar transporter family: a phylogenetic approach.";
RL Biochimie 85:245-260(2003).
CC -!- FUNCTION: Probable sugar transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
CC -!- DOMAIN: The di-lysine motif confers endoplasmic reticulum localization
CC for type I membrane proteins. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ535485; CAD59550.1; -; mRNA.
DR AlphaFoldDB; Q8AWB6; -.
DR SMR; Q8AWB6; -.
DR STRING; 9031.ENSGALP00000016142; -.
DR PaxDb; Q8AWB6; -.
DR VEuPathDB; HostDB:geneid_395185; -.
DR eggNOG; KOG1580; Eukaryota.
DR InParanoid; Q8AWB6; -.
DR PhylomeDB; Q8AWB6; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005460; F:UDP-glucose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0072334; P:UDP-galactose transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013657; UAA.
DR PANTHER; PTHR10778; PTHR10778; 1.
DR Pfam; PF08449; UAA; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..325
FT /note="Solute carrier family 35 member B1"
FT /id="PRO_0000213369"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOTIF 321..325
FT /note="Di-lysine motif"
SQ SEQUENCE 325 AA; 36054 MW; 3D34FE113657BF5A CRC64;
MGANAGRRSR SPERLRLPVC FLGVFACYFY YGILQESITR GKYGDGARQE KFTFALSLVF
IQCVINAAFA KLLIRFFDSV RADRTHSWLY AACSLSYLGA MVSSNSALQF VNYPTQVLGK
SCKPIPVMLL GVTVLRKKYP LAKYLCVLLI VTGVALFMYK PKKGAGGDDH IFGYGELLLL
LSLTLDGLTG VSQDHMRAHY QTGSNHMMLN VNLWSTLFLG AGILFTGELW EFLSFTERYP
SIIYNILLFG LTSALGQSFI FMTVVYFGPL TCSIITTTRK FFTILASVIL FANPISTMQW
VGTVLVFLGL GLDAKFGKGV KKTSH
