S35B1_DANRE
ID S35B1_DANRE Reviewed; 329 AA.
AC Q66HX0;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Solute carrier family 35 member B1;
GN Name=slc35b1; ORFNames=zgc:92284;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable sugar transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
CC -!- DOMAIN: The di-lysine motif confers endoplasmic reticulum localization
CC for type I membrane proteins. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC subfamily. {ECO:0000305}.
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DR EMBL; BC081637; AAH81637.1; -; mRNA.
DR RefSeq; NP_001004583.1; NM_001004583.1.
DR AlphaFoldDB; Q66HX0; -.
DR SMR; Q66HX0; -.
DR STRING; 7955.ENSDARP00000055721; -.
DR PaxDb; Q66HX0; -.
DR Ensembl; ENSDART00000055722; ENSDARP00000055721; ENSDARG00000038213.
DR GeneID; 447844; -.
DR KEGG; dre:447844; -.
DR CTD; 10237; -.
DR ZFIN; ZDB-GENE-040912-148; slc35b1.
DR eggNOG; KOG1580; Eukaryota.
DR GeneTree; ENSGT00940000157900; -.
DR HOGENOM; CLU_036019_1_0_1; -.
DR InParanoid; Q66HX0; -.
DR OMA; VCSNMAL; -.
DR OrthoDB; 1220063at2759; -.
DR PhylomeDB; Q66HX0; -.
DR TreeFam; TF105967; -.
DR PRO; PR:Q66HX0; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 3.
DR Bgee; ENSDARG00000038213; Expressed in tail and 27 other tissues.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005460; F:UDP-glucose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0072334; P:UDP-galactose transmembrane transport; IBA:GO_Central.
DR InterPro; IPR013657; UAA.
DR PANTHER; PTHR10778; PTHR10778; 1.
DR Pfam; PF08449; UAA; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..329
FT /note="Solute carrier family 35 member B1"
FT /id="PRO_0000213370"
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOTIF 325..329
FT /note="Di-lysine motif"
SQ SEQUENCE 329 AA; 36812 MW; 83D7863C4CFF7AFD CRC64;
MAAGKAASKP SLWQNERVRF AVCFCGVFVC YFYYGILQET ITRADYTHAG KKEKFRYATT
LVFIQCIINA AFARLLIQFF EGSKQDHTRS WLYGLCSLSY LGAMVSSNSA LQYVNYPTQV
LGKSCKPIPV MILGVTILRK KYPMAKYLCV FLIVGGVALF LYKPNKGSST SDEHVFGFGE
MLLLLSLTLD GLTGVVQDHM RGRFQTGANH MMLNVNMWST LVLGIAVLWS GEVWEFLAFT
DRYPSIIYNI LLFGITSALG QTFIFMTVVY FGPLTCSIVT TTRKFFTILG SVLLFGNVIS
HMQWFGTILV FLGLGLDAKF GKSPKKTTH
