ID   S35B1_XENTR             Reviewed;         323 AA.
AC   Q8AXS6; Q28HJ6;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Solute carrier family 35 member B1;
GN   Name=slc35b1; ORFNames=TTpA002i04.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND GENE FAMILY.
RX   PubMed=12770764; DOI=10.1016/s0300-9084(03)00046-4;
RA   Martinez-Duncker I., Mollicone R., Codogno P., Oriol R.;
RT   "The nucleotide-sugar transporter family: a phylogenetic approach.";
RL   Biochimie 85:245-260(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tadpole;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable sugar transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- DOMAIN: The di-lysine motif confers endoplasmic reticulum localization
CC       for type I membrane proteins. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAD54627.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ512377; CAD54627.1; ALT_INIT; mRNA.
DR   EMBL; CR760858; CAJ82891.1; -; mRNA.
DR   RefSeq; NP_989418.1; NM_204087.1.
DR   AlphaFoldDB; Q8AXS6; -.
DR   SMR; Q8AXS6; -.
DR   STRING; 8364.ENSXETP00000049605; -.
DR   PaxDb; Q8AXS6; -.
DR   GeneID; 395058; -.
DR   KEGG; xtr:395058; -.
DR   CTD; 10237; -.
DR   Xenbase; XB-GENE-972777; slc35b1.
DR   eggNOG; KOG1580; Eukaryota.
DR   HOGENOM; CLU_036019_1_0_1; -.
DR   InParanoid; Q8AXS6; -.
DR   OrthoDB; 1220063at2759; -.
DR   Proteomes; UP000008143; Chromosome 10.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005460; F:UDP-glucose transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0072334; P:UDP-galactose transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR013657; UAA.
DR   PANTHER; PTHR10778; PTHR10778; 1.
DR   Pfam; PF08449; UAA; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..323
FT                   /note="Solute carrier family 35 member B1"
FT                   /id="PRO_0000213372"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOTIF           319..323
FT                   /note="Di-lysine motif"
SQ   SEQUENCE   323 AA;  35582 MW;  5ACDE8AA88741A4C CRC64;
     MAAGGAQGSG GARLLVCFLG VFVCYFYYGI LQETITRGTY GEGEKQEKFR FALSLVFVQC
     IVNALFAKLL IQFFDSGKTD RTQSWLYAAC SLSYLGAMVS SNSALQFVNY PTQVLGKSCK
     PIPVMLLGVT LLRKKYPLSK YLCVLLIVLG VALFMYKPKN TGSGGDEHTF GYGELLLLLS
     LTLDGLTGVS QDHMRAHFQT GSNHMMLYIN LWSSLFLGAG IVFTGELWDF LSFTERYPSI
     VYNIMLFSLT SALGQTFIFM TVVYFGPLTC SIITTTRKFF TILASVILFS NPISSIQWVG
     TILVFLGLGL DATYGKGSKK PSH